P2. types of junctional complexes.

Question 1

five (5) types of junctional complexes:

Answer 1

1. occluding/ tight juntions
2. adherent junction
3. desmosome/ macula adherens
4. hemidesmosomes
5. gap/ communicating junction

Question 2

• seals adjacent cells to one another
• controls passage of molecules between them
• separates apical & basolateral membrane domains

Answer 2

occluding/ tight junction

Question 3

three (3) major transmembrane link proteins of occluding junction

Answer 3

1. occludins
2. claudins
3. ZO proteins

Question 4

• provides points linking the cytoskeletons of adjacent cells
• strengthens & stabilizes nearby tight junctions

Answer 4

adherent junction

Question 5

two (2) major transmembrane link proteins of adherent junction

Answer 5

1. E-cadherin
2. catenin complexes

Question 6

• provides points of strong intermediate filaments coupling between adjacent cells
• strengthening the tissue

Answer 6

desmosome/ macula adherens

Question 7

major transmembrane link proteins of macula adherens junction

Answer 7

cadherin family proteins:
1. desmogleins
2. desmocollin

Question 8

anchors cytoskeleton to basal lamina

Answer 8

hemidesmosomes

Question 9

major transmembrane link proteins of hemidesmosomes

Answer 9

integrins

Question 10

• allows direct transfer of small molecules & ions from one cell to another
• intracellular communication between adjacent cells

Answer 10

gap/communicating junction

Question 11

major transmembrane link proteins of gap junction

composed of 6 protein subunits

Answer 11

connexin

connexons - communicating channel formed by pairs of abutting particles