P2 Flashcards
the branch of physics that describes the behavior of large objects such as rockets, automobiles, and Ping-Pong balls.
Classical mechanics
the branch of physics that describes the behavior of very small objects, such as x-rays, protons, neutrons, and electrons.
Quantum mechanics
has one proton and one electron and behaves like a bar magnet.
Hydrogen
▪ In an MRI machine, an ____ influences hydrogen atoms, aligning their orientation into parallel (more) or anti- parallel (less). Produces a net magnetization vector (Mz) along the z-axis (longitudinal).
External Magnetic Field (B0)
Each proton spins on its axis like a spinning
top, a motion called ____
precession
Speed of precession
Frequency
The speed of precession (frequency) depends on the strength of the magnetic field (B0) and is defined by the ____
Larmor Equation
: Time for nuclei to realign with the magnetic field (63% recovery).
T1 Relaxation
: Time for nuclei to lose coherence with each other (63% lost).
T2 Relaxation
CHARGED PARTICLE ROTATING AROUND ITS OWN AXIS WITH ANGULAR MOMENT
CLASSICAL MODEL
▪ DESCRIBES HOW THE PARTICLES REACTS TO EXTERNAL MAGNETIC FIELD
QUANTUM MECHANICAL MODEL
According to quantum mechanics, every
nucleus has a quantity called ____
spin
▪ is the ratio of magnetic moment of the
particle to its angular momentum.
Gyromagnetic ratio
The exact frequency of precession by such a nucleus can be calculated with the ___
Larmor equation
IS THE SUM OF ALL THE PROTONS MAGNETIC MOMENT, THUS CALCULATE THE MRI SIGNAL
NET MAGNETIZATION VECTOR
In MRI, the main magnetic field is termed ____
B0
- a phenomenon that occurs when an object is exposed to an oscillating perturbation that has a frequency close to its own natural frequency of oscillation
RESONANCE
- Measures the signal of the coil that is
transverse to our magnetic field
FLIP ANGLE
are patterns of radiofrequency energy used to manipulate the net magnetization of hydrogen nuclei in
MRI.
RF pulse sequences
Determines image contrast, signal strength,
and diagnostic capability.
RF pulse sequences
Alignment of hydrogen nuclei in a magnetic field (B0).
Net Magnetization (M)
Movement of nuclear spins
around the magnetic field.
Precession
: Energy absorption by nuclei at
the Larmor frequency.
Resonance
TYPES OF PULSE SEQUENCE
- ONE-PULSE
- TWO-PULSE
- MULTI-PULSE
- USES 90°-90°- 90°
- Single data are not sufficient to create an
image
SATURATION RECOVERY (SR) PULSE
SEQUENCE
time from the start of one pulse sequence to the start of the next pulse sequence.
REPETITION TIME(TR)
- Uses a 90° pulse followed by a 180°
refocusing pulse. - Produces T1, T2, and PD weighted images.
Spin Echo (SE)
- Employs a single flip angle without 180°
pulse. - Faster imaging with susceptibility effects.
Gradient Echo (GRE)
• Begins with a 180° inversion pulse.
• Enhances contrast for specific tissues (e.g., STIR, FLAIR)
• NO MRI SIGNAL IS CREATED.
Inversion Recovery (IR)
Time between successive RF pulses.
TR (Repetition Time)
Time from RF pulse to signal detection.
TE (Echo Time)
Time from inversion pulse to excitation pulse.
TI (Inversion Time)
: Angle by which M is tipped into the transverse plane
Flip Angle
- Highlights fat and soft tissues.
- Used for anatomical detail.
T1-Weighted Imaging
- Highlights fluid and pathology.
- Used for edema, tumors, and inflammation
T2-Weighted Imaging:
- Distinguishes between structures with
different hydrogen densities.
PD-Weighted Imaging
- STIR for musculoskeletal imaging.
- FLAIR for brain lesions.
Specialized Sequences
- DEFINED AS A PROCESS OF HYDROGEN
NUCLEI LOSING THE ENERGY THEY
ABSORBED DURING EXCITATION
RELAXATION
TYPES of RELAXATION
- SPIN LATTICE (T1 RECOVERY)
- SPIN-SPIN (T2 DECAY)
- RECOVERY OF LONGITUDINAL
MAGNETIZATION
SPIN LATTICE (T1 RECOVERY)
- THE LOSS OR DECAY OF MAGNETIZATION OF MAGNETIC MOMENT IN HYDROGEN NUCLEI IN TRANSVERSE PLANE
SPIN-SPIN RELAXATION (T2 DECAY OR T2
RELAXATION)
- THE METHOD OF ADJUSTING THE EXTRINSIC PARAMETERS TO ENHANCE THE CONTRAST BETWEEN DIFFERENT TISSUES ON IMAGE ON INTRINSIC CONTRAST PARAMETER
WEIGHTING
- EMPHASIZES THE T1 RECOVERY TIME OF
TISSUES EFFECT ON THE IMAGES AND
MINIMIZES T2 DECAY TIMES OF TISSUES
EFFECT ON IMAGE
T1 WEIGHTING (T1W)
- The time it takes for 63% of phase coherence to be lost
T2 DECAY TIME
- USED FOR VISUALIZING PATHOLOGIES AND HIGHLIGHT THE PRESENCE OR LACK
THEREOF FLUIDS
T2 WEIGHTED IMAGES
- FOCUSED ON THE DENSITY OF HYDROGEN PROTONS WITHIN TISSUES, PROVIDING IMAGES THAT REFLECT TRUE
CONCENTRATION OF PROTONS
PROTON DENSITY WEIGHTING
Every nucleus has a quantity called
Spin
Are quantized into units of half-integer values(Spin Quantom Number)
Spins
Dictates many of the MR properties of a giver nuclear species
Spin quantom number
also indicates the limited number of
ways a nucleus can spin
Spin Quantom Number
Is unique for each type of nucleus and must be measured for each.
Gyromagnetic Ratio
this is an empirically determined factor used to convert field strength to processional frequency
Gyromagnetic Ratio
Spin Quantom Number of 1H
1/2
Spin Quantom Number of 13C
1/2
Gyromagnetic Ratio of 1H
42.6
Gyromagnetic Ratio of 13C
10.7
Abundance of 1H
99
Abundance of 12C
98
Abundance of 13C
1.1
a quantity that has direction.
Vector
the view of someone standing
next to the magnet.
Stationary Frame of Reference
Can be observed under the influence of a second magnetic field
Rotating Frame of Reference
Is simply defined as the Sum of the individual nuclear magnetic moments
Net Magnetization
• Strong, very short RF Pulses
• Rotates net magnetization very
strongly
Hard pulses
• Weaker, but longer RF Pulses
• Rotates net magnetization slowly
SOFT PULSES
• Net magnetization at Z-axis
which occurs if a subject is
exposed to the external
magnetic field for a longer
period of time
EQUILIBIRUM (MZ)
• An occurrence in where net
magnetization in the z-axis is
equal to zero and the net
magnetization vector is fully
transferred/observable in the
XY-Axis
SATURATED (MXY)
• Describes the net magnetization
in processing in sync
• Very rarely happens (Close to
impossible) as there is no such
thing as a purely uniform
magnetic field
ON RESONANCE
• Different areas of the imaging
volume has a range of resonant
frequencies
OFF RESONANCE”