P1 PATHOLOGY

Question 1

gaps in myelin sheathes between schwann cells

Answer 1

ranvier nodes

Question 2

which myelin component is similar in PNS & CNS

Answer 2

lipids

Question 2

which myelin component is different in PNS & CNS

Answer 2

Proteins

Question 3

Macrophages role in active neuropathy

Answer 3

removal of axonal & myelin debris

Question 4

mention 2 inflammatory causes of neuropathy

Answer 4

GBS & CIDP

Question 5

Protein synthesis activation for axon regeneration is know as

Answer 5

central chromatolysis

Question 5

incase that nerve regeneration doesn’t happen well , what is the consequence

Answer 5

Traumatic neuroma

Question 6

causes of distal axonopathy

Answer 6

• metabolic : DM & RF
• TOXIC : alcoholism & malnutrition

Question 7

which neuropathy give the characteristic of “ stocking gloves “

Answer 7

distal axonopathy

Question 8

hallmark of demyelinating neuropathy

Answer 8

slowed nerve conduction velocity

Question 9

hallmark of axonopathy

Answer 9

wave of amplitude is affected

Question 10

which disease are the counterparts of MS in CNS

Answer 10

CIDP & GBS

Question 11

clinical symptoms of GBS

Answer 11

Ascending paralysis , change in sensation , weakness

Question 12

identify the disease and comment on the microscopic findings