Oxygen transport in the Blood

Question 1

What is the equation for O2 content of the blood?

Answer 1

O2 content = (O2 binding capacity x % saturation) + dissolved O2

Question 2

What is the normal value for O2 binding capacity?

Answer 2

20.1 mL O2 per 100 mL of blood.

Question 3

What is the equation for O2 delivery to the tissues?

Answer 3

O2 delivery = Cardiac output x O2 content of the blood.

Question 4

What factors cause a right shift of the oxygen Hemoglobin dissociation curve?

Answer 4

right shift is due to decreased affinity of hemoglobin for oxygen

(1) increased Pco2 (decreased pH)
(2) increased temperature
(3) Increase in 2,3 DPG

Question 5

What factors will cause a left shift of the oxygen hemoglobin dissociation curve?

Answer 5

Left shift is due to increased affinity of hemeglobin for oxygen.

(1) Decreased Pco2 (increased pH)
(2) Decreased temperature
(3) Decreased 2,3 DPG
(4) Hemoglobin F