Oxygen therapy Flashcards
whats oxidative phosphorylation
gluxose+O2= CO2+ H2O+ 38 ATP
whats anoxia
no oxygen availability in tissues
whats hypoxia
low/lack of oxygen available in tissues
what is hypoxemia
low/lack of oxygen in the blood
whats FiO2
its the fraction of O2 in inspired gas -21%
what are FiO2 at different litres
1 L/min- 24%
2 L/min- 28%
3 L/min- 32%
4 L/min- 36%
5 L/min- 40%
6 L/min- 44%
what is oxygen therapy
its the administration of oxygen at concs greater than that in the RA to treat/prevent hypoxia
is oxygen a drug
yes
when should oxygen be prescribed
in all situations except for the immediate management of critical illness in accordance with BTS guidelines
what happens if oxygen is abused
can causes complications because of ROS-ALI,ARDS,pulmonary edema
what are the types of hypoxia
hypoxic hypoxia
anemic hypoxia
stagnant hypoxia
histotoxic hypoxia
what causes hypoxic hypoxia
O2 poor air, hypoxic gas mixture
high altitude
hypoventilations
shunts-septal defects
diffusion defects-pneumonia, lobar collapse
what is anemic hypoxia
when oxygen carrying capacity of blood is decreased
what causes anemic hypoxia
anemia
altered hemoglobin- CO poisoning
whats stagnant hypoxia
its when there is inadequate tissue perfusion
what can cause stagnant hypoxia
generalized :
-hypovolemia
-mitral stenosis
-constrictive pericarditis
-myocardial ischemia
localized hypo perfusion:
-arterial obstruction, thrombus, edema
whats histotoxic hypoxia
its when cells can not utilize the oxygen- the electron transfer system of cytochrome oxidase is paralyzed e.g. cyanide poisoning
what are the benefits of O2 therapy in hypoxia
hypoxic hypoxia +++
anemic hypoxia +
stagnant hypoxia +
histotoxic hypoxia -
what are indications for O2 therapy
hypoxia- when PaO2 comes down to 60mmHg
normoxic hypoxia- low cardiac output state, anemia, CO poisoning
trapped gases- like obstruction, pneumoencephalus
special situations- lie anesthesia
what is the clinical presentation of acute hypoxia
restlessness
disorientation, confusion
in-coordination
impaired judgment
hyperventilation air hunger
circulatory changes: tachycardic-brady
whats the clinical presentation of chronic hypoxia
fatigue, drowsiness
inattentiveness
apathy
delayed reaction time
how to measure inadequate oxygen saturation
arterial blood gas
pulse oximeter
what does a low flow O2 delivery system do
they contribute partially to the inspired gas the client breathes
what are examples of low flow systems
nasal cannula
simple mask
non rebreather mask
rebreather mask