Oxygen supply demand Framework Flashcards
What are the 3 determinants of oxygen demand?
Stress(physiologic and perceived), temperature, physical activity
Determinant of contractility
Pre-existing medical condition
What are the Two determinants of preload
-total circulating volume
-venous return
What are the two determinants of Afterload?
-Vessel diameter
-aortic impedance
What are the three determinants of stroke volume?
Contractility, preload, afterload
What are the two main determinants of cardiac output
Stroke volume,
Heart rate
What are the three determinants of oxygen supply?
-Arterial oxygen content
-oxygen transported in the blood
-arterial oxygen saturation
What are the two determinants of oxygen transported in the blood?
Hemoglobin levels
Oxygen hemoglobin affinity
What are the four components of diffusion ?
Driving pressure, diffusion coefficient, anatomical surface area, thickness of A-C membrane
What are the two components of V/Q matching?
Alveolar perfusion, and alveolar ventilation
What are the two components of alveolar gas exchange?
V/Q matching and diffusion
What makes up arterial oxygen saturation?
Alveolar gas exchange and ventilation
What are the tree components that make up “work of breathing”
Respiratory muscle function, lung compliance, airway resistance
What are the four components that make up ventilation
Resp rate
Functional residual capacity
Vital capacity
Tidal volume