oxygen dissociation curve

Question 1

Hemoglobin saturation curve:

Answer 1

-rapid increase in PO2 will occur from 0-60 mmHg
-25% to 30% of blood release the oxygen from hemoglobin

-when PO2 is less than 60mmHg that means there is rapid release of O2
- during excercise during exercise its normal, but during exercise this is indicating hypoxia.

Question 2

Oxygen hemoglobin saturation curve:

Answer 2

-when PO2 is less than 60mmHg that means there is rapid release of O2
- during excercise during exercise its normal, but during exercise this is indicating hypoxia.

venous blood reaches 40 mmHg

Question 3

The bohr effect: oxygen binding affinity is inversly related to low pH and CO2 concentration

Answer 3

Lower pH= hemoglobin saturation decreases because there is more CO2—– shift to the right

Higher pH= hemoglobin saturation increases because, there is less CO2 (less acidic)——- shift to the left

Question 4

A shift to the right indicates an increase in:

Answer 4

-Hydrogen ions- enhance release of O2 and oxygenation

-temperature

-CO2

-BPG= contributes to release of oxygen

Question 5

Combination of hemoglobin with carbon monoxide:

Answer 5

Can displace oxygen’s spot on hemoglobin

has mmHg of 0.4 in alveoli

half of the hemoglobin becomes bound to CO at that point

lethal condition is at 0.6 mmHg

Question 6

Trasnport of CO2 in blood:

3 ways

Answer 6

1) 7% phyisically dissolved in plasma
2) 23% bound to hemoglobin in rbc reversibly HbCO2
3) 70% converterd to bicarbonate ion, HCO3

Question 7

Carbon dioxide dissociation curve:

Answer 7

Normal PCO2 level in arterial blood: 40mmHg
in Venous blood: 45 mmHg

50% volume usually of CO2