Oxford summary 6 Flashcards
Acute Abdomen Hx & Exam
SOCRATES Temperature, pulse, BP, anemia, Jaundice Guarding/ rebound tenderness Rectal/ vaginal examination Urine dipstick/ finger prick blood glucose testing
Acute Abdomen DDx
Renal causes
Gynaecologic
GI
Other
Acute Abdomen
Ruptured spleen Hx
History of trauma
Blood loss: tachycardia, hypotension, pallor
Peritoneal irritation: guarding, rigidity, shoulder tip pain
Paralytic ileus: distention, no bowel sounds
RUQ pain DDx
liver
gallbladder
duodenum
right lung
R Flank pain DDx
R kidney
colon
ureter
MSK
RIF pain DDx
caecum appendix R ovary R fallopian tube ureter
suprapubic pain DDx
bladder
uterus
rectum
epigastric pain DDx
oesophagus
stomach
duodenum
heart
LUQ pain DDx
stomach
spleen
L lung
L Flank pain DDx
L kidney colon ureter AAA MSK
Central pain DDx
small bowel
appendix
Meckel’s diverticulum
LIF pain DDx
colon
L ovary
L Fallopian tube
ureter
Abdominal Pain Hx + Exam
Hx: Socrates
Examination
• Temperature, pulse, BP, RR, anemia, jaundice signs
• Abdominal, rectal, genitalia exam
• Urine dipstick/ finger prick blood glucose testing
Anal/ perianal pain
Fissue, haemorrhoids, naematoma, abscess, fistula Pilonidal sinus Skin infection FunRUQctional pain- proctalgia fugax Carcinoma
tenesmus DDx
IBS
Proctitis
IBD
tumour
Constipation Sx
Straining at defecation ≥25% of time
Tenesmus ≥25% of time
≤2 bowel movements / week
Lumpy/ hard stools ≥25% of time
Constipation Tx
o FBC, ESR, U&E, Cr, LFTs, TFTs, serum glucsose
o Colonoscopy or CT colography if >6weeks
o Lifestyle advice
o Osmotic or bulk- forming laxative- ispaghula, sterculia ± stimulant laxative
o Long- term stimulant laxative: c- danthrustate in very old
o If laxatives not working- try rectal measures. For soft stool- bisacodyl suppositories, if hard stool- glycerin suppositories
Organic causes of constipation
Colonic: cancer, diverticular disease, CD, stricture, intussuption, volvus
Anorectal: ant mucousal prolapse, fissure, abcess, proctitis
Pelvic: ovarian ca, uterine ca, endometriosis
Endocrine: Ca2+, hypothyroid, DM + autonomic neuropathy
Drugs: opioids, antacids + calcium/ aluminum, antidepressants, Fe2+, anti-PD, anticholinergic, anticonvulsants, antihistamine, calcium antagonists
Other: pregnancy, immobility, fluids
Dyspepsia causes
GORD, PU – both 15%
Stomach cancer- 2%
Non-ulcer dyspepsia aka “functiona”- 60%
Oseophagitis
Dyspepsia PC
Retrosternal or epigastric pain
heartburn
Fullness
bloating
wind
N &V
H pylori Tx
Healthy eating, weight loss
Stop smoking, alcohol, caffeine, chocolate, fatty food
omeprazole 20mg bd 4/52 + amoxicillin 1g bd + clarithromycin 500mg bd 1/52
Metronidazole 400mg bd can be used instead of amox
Endoscopy
H. Pylori Dx:
serology,
urea breast test,
faecal antigen test
Gastritis drug causes
Ca antagonists Nitrates Theophyllines Bisphosphonates Corticosteroids, NSAIDs SSRIs
Barret’s oesophagus
Metaplasia into intestinal cell type
Risk of adenocarcinoma
Tx: long-term omeprazole 20-40mg od ± laser ± resection
Acute gastritis
def
types
tx
Mucosal inflammation without ulcer
Type A: entire stomach, a/w pernicious anemia, pre-malignant
Type B: antrum ± duodenum, a/w H.pylori
Type c: due to irritants- NSAIDs, alcohol, bile reflux
Treat cause
Acid suppression with rantidine, nizatidine or PPI 4-8wk
Endoscopy
Gastro-esophageal malignancy upper 2/3
Squamous cell carcinoma
• Smoking, alcohol
• Low fruit and veggies
Gastro-esophageal malignancy lower 1/3
Adenocarcinoma
• Smoking
• Low fruits and veggies
• GORD, obesity
Gastro-esophageal malignancy risks
Previous mediastinal RT
Plummer- Vinson sundrome
Tylosis- inherited. Also hyperkertosis of palms
Gastro-esophageal malignancy PC
Short hx rapidly progressive dysphagia ± weight loss ± regurgitation of food and fluids, hoarsness, cough
Retrosternal pain is late feature
Gastro-esophageal malignancy Tx
endoscopy
CT
RT palliative with stenting tube
Stomach cancer 95% what type age Risks Px: Management:
adenocarcinoma
>55 yo
- Japan, SES
- Blood group A, smoking
- Pernicious anemia, H.pylori, atrophic gastritis
- Adenomatous polyps, previous partial gastrectomy
dyspepsia, weight loss, anorexia, early satiety, V, dysphagia ± GI bleed
endoscopy, total/ partial gastrectomy
Post gastrectomy syndromes
• Early satiety ± weight loss • Bilious vomiting: o Metoclopromide or domperidone • Dumping: distention, colic and vasomotor disturbance after meal= rapid gastric emptying. • Diarrhea: loperamide, codeine • Anaemia: B12 and iron deficiency • Stomach cancer
Colorectal Cancer screening test
faecal occult blood test every 2 years to 60-74years
Colorectal Cancer FHx
risk 2-3x
Refer for colonscopy: 2x first degree or 1x first degree <45
FAP: cancer <40
Juvenile polyposis
Peutz- Jegher syndrome- AD. Benign intestinal polyps with dark freckes on lips, oral mucosa, face, palm and soles
HNPCC: ≥3 relatives with ≥2 generations and ≥1 developed <50
MMR oncogene
Previous hx colorectal cancer
colonoscopy 5 yearly until 70years
Colorectal cancer Risks
Obesity, diet, alcohol, exercise Meds that : HRT, COCP, statins, aspririn Hx gallbladder disease/ cholecystectomy T2DM UC/ Crohns Disease
Colorectal cancer Px:
Bowel habit: D ÷ mucous, constipation or alternating, Tenesmus
Obstruction: pain, distention, absolute constipation ± V
PR bleeding: occult or bright red
Perforation: generalized peritonitis fistula
Systematic
Colorectal cancer Examination and investigation:
General: cachexia, jaundice, anemia
Abdominal mass, hepatosplenomegaly, ascites
Rectal exam
Colorectal cancer Tx:
resection ± chemotherapy
Hemorrhoids “piles”
Def
Risks:
Types
Distention of submucosal plexus of veins at 3,7, 11 o’clock
constipation, Fhx, VV, pregnancy, anal tone, pelvic tumour, portal hypertension
1st degree: piles in anal canal
2nd degree: prolapse out of anal verge but spontaneously reduce
3rd degree: prolapse out of anus and need digital reduction
4th degree: permanently prolapsed
Hemorrhoids “piles”
Px:
Tx
Complications
Discomfort, discharge ± PR bleeding, Tenesmus, pruitius ani
Protoscopy ± sigmoidoscopy if >40 and not visable
Soften stool- bran ispaghula husk
Topical analgesia- lidocaine 5%
Strangulation –> intense pain + anal sphincter spasm
Thrombosis –> pain/ anal sphincter spasm
Perianal haematoma (thrombosed external pile)
Ruptured superficial perianal vein causing subcut haematoma
Px:
Tx:
sudden onset of severe perianal pain
Tender, 2-4mm “dark blueberry” under skin near anus
analgesia, spontaneously settles over 1 week
Rectal prolapse
Young or >60yrars
Px: mass coming from anus ± discharge
Types
Mucosal: 3rd degree- bowel musculature remains in position but redundant mucosa prolapses from anal canal
Complete: decent of upper rectum- weak pelvic floor fro childbirth. Bowel wall inverted and passed
Anal fissure
Torn anal mucosa- posteriorly>
Px:
Management:
Px: pain on defecation ± constipation, PR bleed
Visible as “sentile pile”= bunched up mucosa at base of tear
Rectal examination tender bc muscle spasm
Tx
ispaghula husk, lidocaine 5%, can add glycerol trinitrate 0.4% bd- pain and spasm but can cause headache or 2% topical diltiazem cream bd
Anal ulcers causes
Crohn
Syphilis
Tumour
Anal cancer SCC
Risks
Px:
Tx:
anal sex, syphilis, warts
PRB, pain, anal mass/ulcer, pruritus, stricture, BH change
RT ± CT- if fails then abdominoperineal resection