Ovulation, Conception and Implantation Flashcards
How many chromosomes do oocytes contain?
46
What is the primary oocyte contained within?
The pregranulosa cells, surrounded by the outer basal lamina layer.
What are the three layers of primary follicles?
- Primary oocyte in centre
- Zona pellucida
- Cuboidal shaped granulosa cells
What do granulosa cells secrete? (2)
- Material that becomes zona pellucida
2. Oestrogen
What is the name of the further surrounding layer that primary follicles develop as they grow?
Theca folliculi.
What is the inner layer of the theca folliculi called?
Theca interna.
What does the theca interna secrete?
Androgen hormones.
What is the outer layer of the theca folliculi called?
Theca externa.
What is the theca externa made up of?
Connective tissue cells containing smooth muscle and collagen.
What happens when primary follicles become secondary follicles? (2)
- Grow larger and develop small fluid-filled gaps between the granulosa cells.
- Develop FSH receptors
What happens to create antral follicles?
Secondary follicles develop a single large fluid-filled area within the granulosa cells.
Follicles expand rapidly.
What is the corona radiata in antral follicles?
Corona radiata is made of granulosa cells and surrounds the zona pellucida and oocyte.
What happens when there is a surge in LH from the pituitary? (2)
- Smooth muscle of the theca externa squeeze, and follicle bursts
- Follicular cells release digestive enzymes which puncture hole in wall of ovary.
Describe the location of the ovum immediately after it is released from the ovary.
Floating in peritoneal cavity but is quickly swept up by fimbriae of fallopian tubes.
In the corpus luteum, what do the granulosa and theca interna cells become?
Luteal cells