Overview Of Virology Dr. Enyi

Question 1

Many viruses are stabilised by salts at a conc of?

Answer 1

1mol/L

Question 2

Viruses are stable btw a pH of?

Answer 2

5-9

Question 3

Uv, x-ray and high energy particles inactive viruses.
True/false

Answer 3

True

Question 4

What solubilizes lipid layer of enveloped virus?

Answer 4

Non ionic detergents

Question 5

Examples of Non ionic detergents?

Answer 5

Nonidet p40, Triton x100

Question 6

How does formaldehyde destroy viral infectivity?

Answer 6

By reacting with the nucleic acids

Question 7

Antibacterial antibiotics and sulfonamides have no action on virus
True/false

Answer 7

True

Question 8

The capsid is made up of?

Answer 8

Capsomeres

Question 9

The nucleic acid and capsid make up the?

Answer 9

Nucleocapsid

Question 10

What are the components of the viral envelope?

Answer 10

Phospholipids.
Proteins.
Glycoprotein spikes.

Question 11

What are the functions of viral capsid?

Answer 11

Protects NA.
Aids in transfer to host.
Determines viral symmetry.

Question 12

Examples of enveloped double standard dna virus are??

Answer 12

Herpesviridae
Hepadnaviridae

Question 13

Example of a ssDNA virus is?

Answer 13

Parvoviridae

Question 14

Example of a linear, non enveloped, dsDNA virus is?

Answer 14

Adenoviridae.

Question 15

Examples of a circular, non enveloped dsDNA virus is?

Answer 15

Papillomaviridae.
Polyomaviridae.

Question 16

The only dna virus that isn’t icosohedral is?

Answer 16

Poxviridae

Question 17

Examples of positive sense rna virus include?

Answer 17

Birna,
reo,
orthomyxoviruses,
retrovirus,
paramyxo,
filvo,
bunya,
rhabdo,
arena.

Question 18

Examples of negative sense rna virus?

Answer 18

Corona.
Toga.
Flavi.
Picorna.
Calici.

Question 19

What are the virus under filoviridae?

Answer 19

Ebola

Question 20

Virus under rhabdoviridae?

Answer 20

Rabies

Question 21

Virus under paramyxoviridae?

Answer 21

Measles, mumps, respiratory syncitial virus

Question 22

Virus under orthomyxoviridae??

Answer 22

Influenza

Question 23

Virus under flaviviridae?

Answer 23

Yellow fever, hepatitis c

Question 24

Virus under picornaviridae?

Answer 24

Hepatitis A

Question 25

Virus under caliciviridae?

Answer 25

Hepatitis e

Question 26

What are the stages of viral life cycle?

Answer 26

Attachment.
Penetration.
Uncoating.
Multiplication.
Assembly.
Release.

Question 27

What are the viral factors that affect the virus-host interaction?

Answer 27

Virus strain.
Inoculum size.
Route of exposure.

Question 28

What are the host factors that affect the virus host interaction?

Answer 28

Pre existent immunity from past exposure.

Prior vaccination.

Host genetic factors.

Immune status and age of host.

Question 29

What are the methods of viral entry?

Answer 29

Direct Penetration
Membrane fusion
Endocytosis

Question 30

Enveloped virus penetrate through which means?

Answer 30

Membrane fusion

Question 31

Naked virus penetrates through which method??

Answer 31

Direct Penetration

Question 32

Lysis creates what type of virus?

Answer 32

Naked virus

Question 33

Budding creates what type of virus?

Answer 33

Enveloped virus

Question 34

What are the types of viral release?

Answer 34

Budding.
Exocytosis.
Lysis.

Question 35

Ether susceptibility is used to differentiate btw enveloped and non enveloped virus
True /false

Answer 35

True

Question 36

Which type of virus is more heat labile?

Answer 36

Enveloped virus

Question 37

List the dna viruses?

Answer 37

Herpesviridae
Hepadnaviridae
Adenoviridae
Poxviridae
Papova: papilloma and polyoma
Parvoviridae

Question 38

The negative stranded rna with helical structure is?

Answer 38

Coronaviridae

Question 39

List the viruses with complex symmetry?

Answer 39

Retroviridae and Poxviridae.

Question 40

List the naked dna viruses?

Answer 40

Parvoviridae,
Adenoviridae
Papova

Question 41

List the naked rna virus?

Answer 41

Picornaviridae.
Caliciviridae.
Reoviridae.