Overview of the Nervous system Flashcards
what is the function of the nervous system
- Gather sensory information from the internal and external environment
- Integrate information for assessment and meaning - this happens in the CNS
- Produce a response
- Regulate body homeostasis for optimal performance – ANS
what is the central nervous system made out of
Central nervous system is made out of the brain, brainstem and the spinal cord which is an extension of the brainstem
what does the peripheral nervous system splits into
somatic and autonomic
what does the somatic nervous system do
mainly controls skeletal muscle
what does the autonomic nervous system do
regulates glands, blood vessels and internal organs
what is the autonomic nervous system divided into
sympathetic and parasympathetic
describe afferent neurones
- Afferent – (sensory) – this takes information from PNS to CNS – cell body outside CNS
describe interneurons
- Interneurons – relays information – this is completely imbedded within the CNS, they interconnect between the afferent and efferent neurones
describe efferent neurones
- Efferent (motor) – this takes the response from CNS to PNS – cell body in the CNS
What is the structure of a typical
- Made up of dendrites – these collect information
- Cell body – synthetic centre this is where the neurotransmitters are made
- Axon – this is the conduction pathway, conducts the action potentials from the cell body to other neurones of the effector organ, only have one axon per neurone
- Axon terminal – release neurotransmitter onto other neurones or effector organ
what are the 6 categories of neurones
- Sensory neurone
- Motor neurone
- Preganglionic automimic neurones
- Postganglionic autonomic neurones
- Local interneurons
- Projection neurones (long interneurons)
for every neurone there are…
10 glial cells
what are the glial cells in the PNS
satellite cells
Schwann cells
what is the role of the satellite cells
support cells body
describe the role of the Schwann cells
these make myelin sheath and insulate the axons prevents the action potentials from dissipating
what are the glial cells in the CNS
oligodendrocytes
astrocytes
microglia
ependymal
what do oligodendrocytes do
these make myelin sheath and insulate the axons prevents the action potentials from dissipating
what do astrocytes do
- support cell body and regulate the environment around the neurones,
- they take up potassium, water and neurotransmitters that are in excess,
- they also form the blood brain barrier
what do microglial cells do
these become activated when they are damaged and they phagocytose pathogens that can harm the brain, therefore they act as the immune cells of the brain
what to ependymal cells do
- these are found lining the ventricular system
- they help to move the cerebrospinal fluid around and line the ventricles helping move the CSF around the ventricular system
what is a difference between neurones and glial cells
A neurone cannot go back into the cell cycle, whereas the glial cells can go back into the cell cycle and regenerate themselves
most brain tumours are…
gliomas
why are most brain tumours gliomas
- This is because the glial cells can undergo mitosis and regenerate
- Schwannoma, astrocytoma, ependymoma and oligodendroglioma
what is the most common primary brain tumour in adults
- Glioblastoma multiforme malignant astrocytoma and most common primary brain tumour in adults
what is epilepsy caused by
- Often caused by malfunction in glial cells (astrocyte scar) in a region where neuronal damage has taken place
what causes Alzheimer’s disease
- Tau in astrocytes and oligodendrocytes