Overview of Electron Transport Flashcards
How many pairs of electrons are generated by glycolysis and the TCA cycle?
12 pairs (24 electrons total)
What comprises the glucose oxidation part (first half) of aerobic oxidation?
Glycolysis and the TCA Cycle
What is the second part of aerobic oxidation?
Reduction of O2
What is the product of electron transport and oxidative phosphorylation?
12 H2O
What are the electrons from glucose oxidation transferred to?
NAD+ and FAD (forming NADH and FADH2)
What types of reactions in glucose oxidation yield NADH and FADH2
Oxidation/reduction reactions (dehydrogenase reactions)
What happens to the electrons that are formed from glycolysis and the TCA Cycle?
They are transferred into the mitochondrial electron transport chain
What happens to NADH and FADH2 in the mitochondrial electron transport chain?
They are reoxidized to NAD+ and FAD.
What do the electrons eventually function to do in electron transport?
Reduce O2 to H2O
How many H+ and elecrons enter the second stage of metabolism (electron transport and oxidative phosphorylation)?
24 H+ and 24 electrons
What is the site of electron transfer in glycolysis?
glyceraldehyde-3-phosphate dehydrogenase (2 NAD+ are converted to 2 NADH)
What are the sites of electron transfer in the TCA Cycle (and pyruvate dehydrogenase)?
1) Pyruvate dehydrogenase
2) Isocitrate dehydrogenase (2 NAD+ converted to 2 NADH)
3) alpha-ketogluterate dehydrogenase (2 NAD+ converted to 2 NADH)
4) Succinate dehydrogenase (2 FAD converted to 2 FADH2)
5) malate dehydrogenase (2 NAD+ converted to 2 NADH)
What is the electron transport system?
A set of protein complexes on the inner mitochondrial membrane that contain redox centers.
True or false: Each protein in the electron transport chain has a progressively greater electron affinity.
True
True or false: Electrons move through the electron transport chain from higher to lower standard reduction potentials.
False; from lower to higher standard reduction potentials.
