Overview of circulation of hemodynamic principles Flashcards
(blank) diseases are the leading cause of death in the USA. CV disease is the cause of more deaths than the next (blank) causes of death combined.
CV
5
(blank) is the scientific field concerned with the relationship among the physical principles governing pressure, flow, resistance, and compliance as they relate to the cardiovascular system.
Hemodynamics
Hemodynamics is the scientific field concerned with the relationship among the physical principles governing (blank x 4) as they related to the cardiovascular system
Pressure, flow, resistance, and compliance
The circulation is a (blank) circuit.
closed
The circulation is a complete circuit and features a (blank) pattern.
branching
Blood takes many (blank) from the left heart to the right heart.
parallel pathways
In most cases blood flows through a (blank)
single capillary bed
In most cases blood flows through a single capillary bed (e.g., pulmonary circulation) whereas in other cases the blood flows through (blank)
two capillary beds in series (e.g., kidney).
What is an example of blood flowing through a single capillary bed?
pulmonary circulation
What is an example of blood flowing through two serial capillary beds?
kidney
The circulation is a closed circuit that features what type of flow?
branching patterns with serial and parallel paths
We know blood can flow through a single capillary bed and through capillary beds in series, blood can also flow how?
through an arrangement of parallele and series of paths
Blood flow from the rigght heart to the left heart can only take a (blank) pathway.
single pathway across a single capillary bed in the lungs
Some deoxygenated blood (which should have gone to the right heart mixes with oxygenated blood bound for the (blank) arteries.
system
What type of blood vessels deliver oxygenated blood to the tissues?
arteries
Since heart is a closed system, if you have a problem in one part of the system will it effect the rest of the system?
YES
What type of blood vessel transports the blood under high pressure to the tissues?
arteries
Do all the blood vessels branch?
yes
What blood vessels have strong vascular walls?
arteries
What blood vessels have rapid pulsatile blood flow?
arteries
What blood vessels are densely innervated?
arteries
Arteriolar resistance is regulated by (blank)
ANS
What type of adrenergic receptors mediate vasoconstriction on the arterioles of the skin, splachnic, and renal circulation?
alpha-1
What type of adrenergic receptors mediate vasodilation and are found on arterioles of skeletal muscle and in small coronary arteries?
Beta-2
What are the smallest branches of the arteries that are 5-100 micron diameter?
arterioles
What are the major resistance vessels of the whole peripheral circulation?
arterioles
What blood vessels have thick smooth muscle layer?
arterioles
What blood vessels have endothelial cell layer and are very densly innervated?
arterioles
What type of blood vessels regulate blood flow to the capillary beds and have the biggest pressure drop?
arterioles
What are the stopcocks of the circulation?
arterioles
What blood vessels have smooth muscle that are partially contracted under normal conditions (basal tone)?
arterioles
What type of blood vessels have basal tone?
arterioles
What are the main resistance blood vessels? (target these when dealing with blood pressure)
arterioles
Factors that control blood flow to the capillaries do so by (blank)
vasoconstriction and vasodialation
In order to vasconstrict, you need vessel that is (blank)
not fully constricted to start with
In order to vasodilated, you need a vessel that is (blank)
not fully relaxed to start with
The smooth muscle surrounding the resistance vessels therefore have (blank).
Basal tone (some level of tonic contraction)
What is basal tone?
the consistant slight vasoconstriction of arterioles
In contrast to skeletal muscle (which is under nerves control), vascular smooth muscle has some tone without needing (blank).
Neural input
The basal tone in arterioles probably comes from (blank)
intrinsic and local factors
What blood vessels are the smallest (5-10 micron diameter) with NO smooth muscle?
capillaries
Do capillaries have smooth muscle?
no
What blood vessels have very thin walls consisting of a single layer of endothelium permeable to small substances?
capillaries
What are the major exchange vessels?
capillaries
What blood vessels have the largest cross-sectional area?
capillaries (combined cross sectional area, singular cross sectional area are small but together really big)
What blood vessels have low flow velocity?
capillaries
Can white cells squeeze out of between cells of capillary?
YES!
What are small vessels (20 microns) with thin walls?
venules
What blood vessels collect blood from capillaries and participate in exchange?
venules
Do venules participate in exchange?
yes
What blood vessels gradually coalesce into progressibely larger veins and the total cross-sectional area diminshes here and the velocity of blood flow increases?
venules
What blood vessels merge to form larger veins and transport blood from tissues back to the heart?
veins
What blood vessels are major capacitance vessels=major collection and storage site for blood (major controllable reservoir)
veins
What blood vessels have thing BUT muscular walls?
veins
What blood vessels are under low pressure and are densely innervated?
veins
About 85% of the entire blood volume of the body is in the (blank) , and about 15% in (blank). Of the 85 % in the systemic circulation, ~65% is in the veins, ~13% in the arteries, and ~7% in the systemic arterioles and capillaries.
systemic circulation
heart and lungs