Histology of Circulatory System Flashcards

1
Q

What are the three layers of a blood vessels?

A

tunica intima, tunica media, tunica adventita

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What does the tunica intima do?

A

It makes up the endothelium and immediate surroundings of it (simple squamos except in lymphnode high endothelial venules which are cuboidal)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What makes up the tunica intima?

A

endothelium (simple squamos epithelium), variable basal lamina of endothelium, subendothelial connective tissue, internal elastic lamina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the endothelium of blood vessels made of?

A

simple squamos epithleium except in high endothelial venules, they are cuboidal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What allows for communication between the tunica intima and the tunica media?

A

internal elastic lamina that is fenistrated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the active layer of the blood vessel that is filled with smooth muscle cells and can sometimes have an external elastic lamina?

A

Tunica media

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What does the tunica adventitia do?

A

connective tissue that relates to other blood vessels and organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Is the basal lamina of a blood vessel cellular or acellular?

A

acellular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the basal lamina made of?

A

collagen and glycoprotein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Simple squamos epithelium are oriented what way to blood flow?

A

parallel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What try to inhibit coagulation at times and aid blood flow but all are metabolically active to help secrete substances to create CT (collagen, laminin)?

A

simple squamos epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What does simple squamos epithelium secrete in the relaxed state?

A

NO to cause vasodiliation to allow for open blood low

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What does simple squamos epithelium secrete in the constricted state?

A

Endothelin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

All endothelial cell smake what factor to help with clotting?

A

von willebrand factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Most arteries have special storage bodies called (blank) and they are full of von willebrand factors.
When are these factors released?

A

Weibel Palade bodies.

Damage to blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are embedded in the endothelium?

A

enzymes such as angiotensin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Simple squamos epithelium secrete substances related to (blank).

A

structure, hemodynamics and clotting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What does the Tunic Media consist of?

A

Smooth muscle and external elastic lamina

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What does the Tunica adventitia make up?

A

CT surrounding the Tunica media; and vaso vasorum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What responds to substances secreted by endothelium? What responds to nerve stimuli?

A

tunica media, tunica media (leads to vasoconstriction and dialation)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Do ALL arteries have an external elastic lamina?

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What is the tunica adventitia made out of?

A

fibroblasts, collagen, elastic tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Where do vasa vasorum travel and nerves travel?

A

Tunica adventitia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

For most blood vessels, constriction will occur with sympathetic stimulation except for coronary arteries and (blank).

A

skeletal muscle vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What is complex and involves pituitary, kidneys, baroreceptors, and sympathetics?
regulation of blood pressure
26
When nerves of the tunic adventitia are stimulated, what happens?
they release neurotransmitters which diffuse through fenestre in the external elastic lamina and stimulate outter most layer of smooth muscles which propogate the signal to other smooth muscle cells via gap junctions
27
What cells are spindle shaped and can have a nerve traveling on top of it?
smooth muscle in blood vessels
28
When will you not see a fenestrated internal elastic lamina?
in small and terminal arterioles
29
Which need more vaso vasorum, veins or arteries?
veins
30
What are the three types of arteries?
elastic, muscular and arteriole
31
What are the conducting arteries that stretch and recoil
elastic arteries
32
What arteries have prominent vasa vasorum and 40-70 elastin lamellae?
elastic arteries
33
What are the elastic arteries?
pulmonary trunk, aorta, common carotid, subclavian, common iliacs
34
How many layers of smooth muscle and elastin do elastic arteries have?
40-70 layers
35
Do elastic arteries have a lot of loose connective tissue?
yes so they can stretch
36
Most arteries with a name are what kind of arteries?
muscular arteries
37
Do muscular arteries have a large smooth muscle cell layer?
Yes very large
38
Do muscular arteries have internal and external elastic lamina?
yes and they are fenestered
39
Are there elastic fibers in muscular arteries?
no
40
What are more dense, elastic arteries or muscular arteries?
muscular
41
Where are gap junctions located in blood vessels?
between smooth muscle cells
42
Where do you see more vaso vasorum, in elastic or muscular arteries?
elastic
43
What are the distributing arteries and have a large smooth muscle layer, contain gap junctions and have prominent Internal elastic layer and external elastic layer?
Muscular arteries
44
What are terminal arteries?
arterioles
45
What type of arteries have poorly defined internal elastic layer and do not need vasa vasorum?
arterioles
46
What have metarterioles which have discontinuous tunica media?
arterioles
47
What has a vessel wall as big as the diameter of its lumen?
arterioles
48
Do arterioles have a vaso vasorum?
No
49
What do metarterioles help with?
control of blood flow
50
What are thin and have endothelial cells and basal lamina which sometimes have a nucleus and a red blood cell. Pericytes are sometimes associated with these. Main function is to transport gases and nutrients. 50 mm in length (short and thin)
Capillaries
51
How can you tell arteries and veins apart?
arteries are circular do to robust tunica media, veins are all irregular shaped and thin wall (not a lot of smooth muscle)
52
Which are bigger, veins or arteries?
veins
53
What are the three types of capillaries?
continuous (somatic),fenestrated (visceral) capillaries, sinusoidal capillaries
54
Where are continous (somatic) capillaries found? (material transveres the endthelial cell in either direction via pinocytotic vesicles)
Found in nervous tissue, brain tissue, and muscle tissue
55
Where are fenestrated capillaries found?
found in pancreas, endocrine glands, and intestines, modified from in glomerulus of kidney
56
Where are sinusoidal capillaries found? (biggest capillaries)
spleen, liver, bone marrow ( macrophages reach into capillary and grab bad stuff out of capillary)
57
Which kind of capillary has no basal lamina?
sinusoidal capillaries in liver
58
What kind of capillaries have a large lumen, possess numerous fenestrae have discontinous basal lamina and lack pinocytotic vesicles, often have overlapping endothelial cells.
sinusoidal (discontinous) capillary
59
When blood needs to be controlled from one arteriole to a venule bypassing a capillary, a vessel with an incomplete smooth muscle coat helps along with a precapillary sphincter.
Metarteriole
60
When would you utilize a metarteriole?
heat loss
61
What cells are associated with capillaries and form gap junctions and if injury occurs, can become smooth muscle cell or endothelial cell and can regulate blood flow?
pericytes
62
In veins, the tunica media is thinner or thicker than arteries?
thinner
63
Are there valves in veins? Is there vaso vasorum?What are they made out of?
some, Yes a lot more than arteries, extensions of endothelium ( easy for them to become damaged)
64
Are there valves in arteries? What are they made out of?
no, extnsions of endothelium ( easy for them to become damaged)
65
The tunica media is much more prominent in the legs, why?
Because it is really hard to go against gravity so you need more help from the connective tissue
66
What do venules and capillaries have in common?
they both have pericytes
67
What are they perferred site for WBC migration (diapedesis)?
venules
68
What are more permeable, capillaries or venules?
venules
69
Do all venules have simple squamos epithelium?
no just most
70
Where do you have special WBC migration and what type of venules help out there?
lymph nodes, high endothelial venules with CUBOIDAL endothelium
71
What makes up the tunica media in veins?
smooth muscle and fibroelastic connective tissue
72
What has collagenous connective tissue, fibroblasts, elastic fibers and vaso vasorum?
Tunica Adventitia
73
What is continous with the lining of the chambers of the heart and comes from aorta?
endothelim (endocardium/simple squamos epithelium)
74
What is just outside the endocardium and has purkinje fibers?
sunendocardial connective tissue
75
What is the tunica media of the heart?
myocardium
76
What is the tnica adventitia of the epicardium?
visceral pericardium
77
What is neat about myocardium?
structure, contraction, conduction, endocrine
78
Does the myocardium ever rest?
no, continual contraction
79
What is connected to myocardium and gives heart distinct and permanent structuer?
fibroskeleton
80
What is the endocrine function of the heart?
it influences fluid control and blood pressure and is a dynamic tissue
81
If you have damaged heart muscle MI, Ischemia) what proteins will you see?
troponin, BNP
82
What is the flow and pump structure of lymphatic vessels?
one way flow, no pump
83
What does the lymphatic system do>
takes fluid collecting in interstitial fluid of cells back into vascular system
84
Is the lymphatic system high or low pressure?
low
85
What are the simplest and smallest vessels in the lympathic system?
lymphatic capillaries
86
describe the structure of a lymphatic capillary?
starts in tissue somewhere and has endothelial cells overlap each other to create loose connections that allow fluid to leak in and out.
87
What is the lymphatic system dependent on?
gravity
88
Since the lymphatic vessels are so thin, how are they connected to adjacent connective tissue?
with lymphatic anchoring filaments
89
Lymphatic capillaries go to lymphatic vessels which go where?
into lymphatic duct and thoracic duct into large veins in the next
90
What are the 3 layers of the lymphatic ducts?
TI,TM,TA
91
What is this: TI:have endothelium, basal lamina, valves in some, subendothelial connective tisssue TM: connective tissue and smooth muscle cells TA: Smooth muscle cells oriented in longitudinal bundles; cardiac muscle cells near their entry into the heart, collagen layers with fibroblasts.
large veins
92
What is this: TI: endothelium, basal lamina, valves in some, subendothelial connective tissue TM: reticular and elastic fibers and smooth muscel cells TA: collagen layers with fibroblasts
Medium and small veins
93
What is this TI: endothelium and basal lamina and pericytes TM: sparse connective tissue and a few smooth muscle cells TA: some collagen and a few fibroblasts
Venules
94
What is this: TI: endothelium w/ weibel-palade bodies, basal lamina, subendothelial layer, incomplete internal elastic lamina TM 40-70 fenestrate elastic membranes; smooth muscle cells intersperesed between elastic membranesl thin external elastsic lamina;vaso vasorum in outer half TA thin layer of fibroelastic connective tissue, vasa vasorum, lymphatic vessels, nerve fibers.
Elastic Artery
95
What is this: TI: Endothelium w/ weibel-palade bodies, basal lamina, subendothelial layer, thick internal elastic lamina TM: Up to 40 layers of smooth muscle cells; thick external elastic lamina TA: thin layer of fibroelastic connective tissue; vasa vasorum not very prominent; lymphatic vessels; nerve fibers
Muscular artery
96
What is this: TI: endothelium with Weibel-Plalade bodies, basal lamina, subendothelial layer not very prominent; some elastic fibers instead of a defined internal elastic lamina TM: 1 to 2 layers of smooth muscle cells TA loos connective tissue, nerve fibers
Arteriole
97
What is this: TI, endothelium,basal lamina TM: smooth muscle cells form precapillary sphincter TA:sparse loose connective tissue
metarteriole
98
all type of veins have fibroblasts, do arteries?
no