Histology of Circulatory System Flashcards
What are the three layers of a blood vessels?
tunica intima, tunica media, tunica adventita
What does the tunica intima do?
It makes up the endothelium and immediate surroundings of it (simple squamos except in lymphnode high endothelial venules which are cuboidal)
What makes up the tunica intima?
endothelium (simple squamos epithelium), variable basal lamina of endothelium, subendothelial connective tissue, internal elastic lamina
What is the endothelium of blood vessels made of?
simple squamos epithleium except in high endothelial venules, they are cuboidal
What allows for communication between the tunica intima and the tunica media?
internal elastic lamina that is fenistrated
What is the active layer of the blood vessel that is filled with smooth muscle cells and can sometimes have an external elastic lamina?
Tunica media
What does the tunica adventitia do?
connective tissue that relates to other blood vessels and organs
Is the basal lamina of a blood vessel cellular or acellular?
acellular
What is the basal lamina made of?
collagen and glycoprotein
Simple squamos epithelium are oriented what way to blood flow?
parallel
What try to inhibit coagulation at times and aid blood flow but all are metabolically active to help secrete substances to create CT (collagen, laminin)?
simple squamos epithelium
What does simple squamos epithelium secrete in the relaxed state?
NO to cause vasodiliation to allow for open blood low
What does simple squamos epithelium secrete in the constricted state?
Endothelin
All endothelial cell smake what factor to help with clotting?
von willebrand factor
Most arteries have special storage bodies called (blank) and they are full of von willebrand factors.
When are these factors released?
Weibel Palade bodies.
Damage to blood vessels
What are embedded in the endothelium?
enzymes such as angiotensin
Simple squamos epithelium secrete substances related to (blank).
structure, hemodynamics and clotting
What does the Tunic Media consist of?
Smooth muscle and external elastic lamina
What does the Tunica adventitia make up?
CT surrounding the Tunica media; and vaso vasorum
What responds to substances secreted by endothelium? What responds to nerve stimuli?
tunica media, tunica media (leads to vasoconstriction and dialation)
Do ALL arteries have an external elastic lamina?
no
What is the tunica adventitia made out of?
fibroblasts, collagen, elastic tissue
Where do vasa vasorum travel and nerves travel?
Tunica adventitia
For most blood vessels, constriction will occur with sympathetic stimulation except for coronary arteries and (blank).
skeletal muscle vessels