Overview Flashcards
Krebs Cycle is aka?
Tricarboxylic Acid Cycle (TCA)
Citric Acid Cycle
The metabolic hub
Where is the Krebs cycle located?
Mitochondrial matrix
Krebs occurs under what types of conditions?
aerobic
The substrates for the Krebs cycle are the breakdown products of what?
Carbohydrates
Fats
Protein metabolism
The MAIN FUEL used to drive Krebs cycle is?
Acetyl CoA
What end product of carbohydrate metabolism is turned into acetyl CoA?
pyruvate
Each Acetyl CoA generated from pyruvate is used to produce ? from the Krebs cycle?
3 NADH
1 FADH2
1GTP
2 CO2
When the two molecules of pyruvate are converted to acetyl groups, they lose what?
CO2
Each acetyl group is activated by which carrier molecule? To form what?
Coenzyme A
Acetyl CoA
What enzyme is responsible for making acetyl CoA from acetyl group and Coenzyme A?
Pyruvate dehydrogenase complex
Where is pyruvate dehydrogenase complex located?
mitochondria
The ___ carbon acetyl CoA is joined with what 4 carbon molecule? What doe the make?
2
4 carbon oxaloacetate
6 carbon citrate
How many steps are in Krebs cycle?
8