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MyNBCE - Biochemisty - Krebs Cycle > 8 steps > Flashcards

8 steps Flashcards

1
Q

What is a mnemonic for Krebs?

A

Can I Keep Selling Sex For Money, Officer?

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2
Q

1st step - (Can)

A

Citrate is form from acetyl CoA and oxaloacetate.

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3
Q

What is the enzyme for step 1?

A

Citrate synthase

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4
Q

What inhibits citrate synthase?

A

ATP!

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5
Q

2nd Step (I)

A

Isocitrate is produced from citrate

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6
Q

Enzyme for step 2?

A

aconitase

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7
Q

Step 3 - (Keep)

A

alpha-ketoglutarate is produce from isocitrate

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8
Q

Enzyme used in Step 3?

A

Isocitrate dehydrogenase

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9
Q

What is the rate limiting enzyme in Krebs?

A

Isocitrate dehydrogenase (step 3)

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10
Q

What activates isocitrate dehydrogenase?

A

ADP

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11
Q

What inhibits isocitrate dehydrogenase?

A

ATP and NADH

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12
Q

One ______ is produced in the 3rd step.

A

NADH

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13
Q

One molecule of what is released in the 3rd step.

A

CO2

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14
Q

4th step (Selling)

A

succinyl CoA is produced from alpha-ketoglutarate

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15
Q

What enzyme is used in 4th step?

A

alpha-ketoglutarate dehydrogenase

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16
Q

What doe alpha-ketoglutarate require?

A

Vitamin B1 - thiamine
Vitamin B2 - riboflavin
Vitamin B3 - Niacin
Vitamin B5 - Pantothenic Acid

17
Q

What molecule is produced and what molecule is released in step 4?

A

One NADH

one CO2

18
Q

Step 5 (Sex)

A

Succinct is produced from succinyl CoA

19
Q

What enzyme catalyzed step 5 reaction?

A

Succinct thiokinase aka succinyl CoA synthetase

20
Q

One high energy ____ is produce in step 5.

A

GTP

21
Q

GTP can react with what? To make what?

A

ADP

ATP

22
Q

6th Step: (For)

A

fumarate is produce from succinate

23
Q

What is enzyme for step 6?

A

Succinate dehydrogenase

24
Q

What is the only TCA cycle enzyme bound to the mitochondrial membrane instead of being soluble in the mitochondrial matrix?

A

succinate dehydrogenase

25
Q

Succinate dehydrogenase is the only TCA cycle enzyme that directly uses what?

A

FAD

26
Q

What molecule is produced in step 6?

A

1 FADH2

27
Q

What is the non-protein part of a conjugated protein called?

A

prosthetic

28
Q

FAD is a covalently-bounded ________ group.

A

prosthetic

29
Q

Step 7 (Money)

A

Malate is produced from fumarate

30
Q

What enzyme converts fumarate into Malate in step 7?

A

fumarase

31
Q

Step 8 (officer)

A

Oxaloacetate is produced from malate

32
Q

Enzyme used for step 8? Conversion of Malate into oxaloacetate.

A

Malate dehydrogenase

33
Q

Is step 8 reversible?

A

YES

34
Q

Oxaloacetate is added to what to re-enter the Krebs cycle?

A

Acetyl CoA

35
Q

What molecule is produce at stage 8?

A

One NADH

MyNBCE - Biochemisty - Krebs Cycle (5 decks)

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