Overall Flashcards
What are the lab values for MEN2B?
- Increased Calcitonin (check for thyroid cancer)
- Increased urinary VMA with pheochromocytomas
What are the lab values for MNTI?
- Increased VMA in urine
- Normalizes with tumor excison
In what disease are tramline calcifications seen on skull film?
Sturge-Weber Syndrome (Encephalotrigeminal Angiomatosis)
What lesion’s surface resembles translucent vesicles, similar to “frog eggs”?
Lymphangioma
What lesion’s histology shows, spindle-shaped cells with cigar-shaped nuclei (rounded ends)?
Leiomyoma
What lesions can look like a bunch of grapes, “botryoid”?
Rhabdomyosarcoma
Oral involvement is seen most frequently in what forms of Leukemia?
Myelomonocytic
What disease has the classic symptom of a medastinal mass = massive enlargement on the midline of lungs?
Hodgkin Lymphoma
What disease uses presence of reed-sternburg cells for diagnosis?
Hodgkin Lymphoma
large, multi- or bilobed nucleus; “owl eye”
What disease shows a “starry sky” histo pattern?
Burkitt Lymphoma
What are the lab values for Multiple Myeloma?
Elevation in:
- IgM protein
- Bence-jones proteins (light chain)
- Heavy chains
What disease uses a CD1a marker for its cells?
Langerhans Cell Histiocytosis
What is seen on the EM of Langerhans Cell Histiocytosis?
Birbeck granues
(tubules)
What is the characteristic histology of Sjogren’s Sx?
Benign Lymphoepithelial Lesions
- Lymphocytic infiltrate
- Parenchyma destruction (by lymphocytes)
- Epimyoepithelial islands
What are the lab values associated with Sjogren sx?
- Serologic increases in:
- Rheumatoid factor
- ANA
- Erythrocyte sed rate
- + Anti-SS-A (Ro) or + Anti-SS-B (La) Antibody