Overall Flashcards
What are the lab values for MEN2B?
- Increased Calcitonin (check for thyroid cancer)
- Increased urinary VMA with pheochromocytomas
What are the lab values for MNTI?
- Increased VMA in urine
- Normalizes with tumor excison
In what disease are tramline calcifications seen on skull film?
Sturge-Weber Syndrome (Encephalotrigeminal Angiomatosis)
What lesion’s surface resembles translucent vesicles, similar to “frog eggs”?
Lymphangioma
What lesion’s histology shows, spindle-shaped cells with cigar-shaped nuclei (rounded ends)?
Leiomyoma
What lesions can look like a bunch of grapes, “botryoid”?
Rhabdomyosarcoma
Oral involvement is seen most frequently in what forms of Leukemia?
Myelomonocytic
What disease has the classic symptom of a medastinal mass = massive enlargement on the midline of lungs?
Hodgkin Lymphoma
What disease uses presence of reed-sternburg cells for diagnosis?
Hodgkin Lymphoma
large, multi- or bilobed nucleus; “owl eye”
What disease shows a “starry sky” histo pattern?
Burkitt Lymphoma
What are the lab values for Multiple Myeloma?
Elevation in:
- IgM protein
- Bence-jones proteins (light chain)
- Heavy chains
What disease uses a CD1a marker for its cells?
Langerhans Cell Histiocytosis
What is seen on the EM of Langerhans Cell Histiocytosis?
Birbeck granues
(tubules)
What is the characteristic histology of Sjogren’s Sx?
Benign Lymphoepithelial Lesions
- Lymphocytic infiltrate
- Parenchyma destruction (by lymphocytes)
- Epimyoepithelial islands
What are the lab values associated with Sjogren sx?
- Serologic increases in:
- Rheumatoid factor
- ANA
- Erythrocyte sed rate
- + Anti-SS-A (Ro) or + Anti-SS-B (La) Antibody
What are the lab values associated with Ig-G4-Related Ds?
- Elevated:
- Serum IgG4
- IgG4-producing plasma cells
Most Common Reportable BACTERIAL infection
Gonorrhea
Most common cause of chronic regional lymphadenopathy in children
Cat Scratch Disease
Most common oral fungal infection
Candidiasis
Most common systemic fungal infection in U.S
Histoplasmosis
Most common Peripheral Nerve Tumor
Neurofibroma
One of the most common autosomal genetic problems that affects humans
Neurofibromatosis
Most common site of Salivary gland tumors
Parotid (superficial lobe 80%)
Most common site for minor salivary gland tumors
Palate
Most common malignancy of parotid gland
Mucoepidermoid Carcinoma
Most common malignancy of submandibular gland
Adenoid Cystic Carcinoma
Most common salivary gland tumor in infants
Hemangioendothelioma of Parotid
Most common primary salivary gland tumor (benign epithelial tumor) to develop during childhood
BMT - Pleomorphic Adenoma
Most common salivary malignancy in children?
MEC
Most common tumor of infancy
Hemangioma
What tumor is most common in the uterus
Leiomyoma
What tumor is most common in the Heart?
Rhabdomyoma
Rarest salivary neoplasm
Oncocytoma (Oxyphil Adenoma)
Most common type of malignant SGT
MEC
Most common Malignant Mixed Tumor
Carcinoma ex Mixed Tumor
Another name for mumps
parotitis
