5. Soft Tissue Developmental Lesions Flashcards
What is the DD of Macroglossia due to Neoplasms and Hamartomas?
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Hemangioma
Lymphangioma
Neurofibroma (NF)
Schwannoma
MEN 2B/3
What is the DD of Macroglossia due to Endocrine?
Myxedema/Cretinism
Acromegaly
What is the DD of Macroglossia due to Other Developmental/Genetic?
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Congenital
Hemihypertrophy
Down Syndrome
Mucopolysacharidoses
Beckwith Hypoglycemia Sx
What is the DD of Macroglossia due to Acquired Reasons?
Amyloidosis (multiple myeloma)
Physiologic - loss of teeth
- Scalloped edges are aquired and due to constant pressure of tongue against lingual surfaces of teeth
- Can cause Burning Mouth
Crenated Tongue
What is the major associated factor causing Fissured Tongue?
Geographic Tongue (BMG)
Most common site of Geographic Tongue (BMG)
anterior dorsolateral tongue
What will the biopsy of BMG yeild histologically?
- Neutrophilic Munro micro-abscesses
- Elongation of rete ridges
Besides BMG what else is Fissured Tongue associated with?
Melkersson-Rosenthal Sx
What looks like Geograhic Tongue but on the soft palate, and requires presence of typical tongue Geographic Tongue to be dx?
Migratory Stomatitis
Red, depapillated patch on midline, posterodorsal tongue (rare site of cancer)?
Median Rhomboid Glossitis
What was the theorized etiology of Median Rhomboid Glossitis?
Developmental failure of tuberculum impar to disappear
proven non-developmental (not in children)
Some cases of what disease have kissing lesions in soft palate that represent candida or hypersensitivity rxn to candida antigens. CITNIP
Median Rhomboid Glossitis
What does the Histology of Median Rhomboid Glossitis Show? (4)
- Absence of papilla
- Chronic inflammation
- Candida in parakeratin
- PEH
What is the discoloration of Hairy Tongue from?
- Chromphilic organisms
- Fe sulfide from bact reduction
- Tobacco, coffee, tea