Overactive Bladder

Question 1

What is over active bladder

Answer 1

It’s a false signal from the bladder telling you that it’s full and you need to empty your bladder
The bladder starts to contract early before it full, or reached it’s maximum capacity.

Question 2

What are the name of the medicine given in stress incontinence and it’s side effects

Answer 2

Duloxitin: anti depression
Works by increasing the amount of mood enhancing chemicals in the brain.
Side effects: sickness, dry mouth, constipation headache, feeling sleepy.
Don’t stop by your self
Needs to stop gradually to avoid withdrawal symptoms
It’s used 2nd line management

Question 3

Important points to ask in stress incontinence

Answer 3

Latex allergy

Question 4

Name of medicine in overactive bladder

Answer 4

Anticholonergic medication
Oxybutinin
Toteradine
Darfenacin

Question 5

Side effects of anti cholonergic?

Answer 5

Dry mouth constipation
Headache
Flushed skin
Rapid heart beat
Affect cognitive function
Long term memory problems

Question 6

Action of Mirabegron

Answer 6

Mirabegron is a potent and selective agonist of beta-3 adrenergic receptors. The activation of beta-3 receptors relaxes detrusor smooth muscle during the storage phase of the urinary bladder fill-void cycle, which increases the bladder’s storage capacity thereby alleviating feelings of urgency and frequency.

Question 7

Important points with oxybutinine

Answer 7

Avoid alcohol
Contra indicated :

Question 8

Options of over active bladder

Answer 8

Oxybutini, antimuscrin medication avoid alcohol
Patch
Mirabegron
Botox 10-15 in 100 of women
Per cutaneous sacral nerve stimulation.
Percutanous posterior tibial nerve stimulation.
Will coordinate your bladder
Augmentation cystoplasty

Question 9

Options of management of over active bladder

Answer 9

• Anticholinergics (provided she has no contraindications)
  Mode of action
  Names: Oxybutynin, Tolterodine, Darifenacin
  Side effects: dry eyes/mouth, constipation. Rapid heartbeats, heartburn, flushed skin.
  Memory issues on the long run “uncertain”
  4 weeks to see the effect, symptoms continue to improve over time
  Follow up visit after 4 weeks, earlier if cannot tolerate the side effects.
  Side effects not tolerated: change the route
  -+ Continue bladder training with the specialist nurse.
  Further options: (BRIEFLY)
  _ Mirabegron
• Urodynamics, MDT
• Botulinum toxin OR
• Percutaneous sacral nerve stimulation OR
• Percutaneous Posterior tibial nerve stimulation

Question 10

Function of Botox

Answer 10

Botox to numb and slow the contractions of bladder
Device that gives signal to bladder to slow it down