1
Q

Follicular development before ovum release

A
  1. Primary follicle
    - Best one selected to develop
  2. Early antrum
  3. Atretic follicle
  4. Graafian follicle.
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2
Q

Corpus luteum

A

Structure in the ovary that secretes progesterone after ovum release.

After it matures, and secretes progesterone, becomes corpus albicans

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3
Q

Corpus albicans

A

Scar tissue of degenerated corpus luteum.

Non-functioning/

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4
Q

Epidemiology

  • Gynae admission
  • % of women in UK admitted by 65
A

4th most common gynae admission

4% of women in UK admitted by 65

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5
Q

Complications of ovarian cysts

A

Torsion

Rupture

Haemorrhage

Infection

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6
Q

Ovarian torsion

  • Description
  • Presentation
A

Occurs when the ovaries becomes twisted around vascular pedicle.

Presentation

  • Acute abdominal pain
  • Nausea/ vomitting
  • Tachycardia
  • Guarding, rigidity
  • Ovary can be rotated higher into abdomen
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7
Q

Ovarian torsion

  • Complication
  • Management
A

Infarction of the ovaries
- Ovarian necrosis

Salpingo-oophorectomy surgery

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8
Q

Ovarian cyst rupture

  • Presentation
  • Treatment
A

Cyst can rupture spontaneously or as a result of trauma.

Can present with vague/ sharp pain

  • Lower abdominal pain
  • Tenderness and guarding
  • USS free fluid

Treatment
- If mild consequences- conservative management

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9
Q

Ovarian cyst haemorrhage

  • Presentation
  • Treatment
A

Acute lower abdo pain
- Minial abdo symptoms

USS- haemorrhage into cysts

Conservative or operative treatment depending on symptoms and bleeding

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10
Q

Ovarian cyst rupture sequelae

A

Peritonitis

Pseudomyoxma peritonei

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11
Q

Dermoid ovarian cyst

A

Benign tumour that develops from totipotential germ cell (primary oocyte)
- Contains all the 3 germ cell layers (mesoderm, endoderm, ectoderm

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12
Q

Dermoid ovarian cyst

- Presentation

A

If it grows large

  • Fullness in pelvis
  • Deep dysparunia
  • Increasing urinary frequency

Diagnoses confirmed with USS

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13
Q

Dermoid ovarian cyst management

A

Laparoscopic ovarian cystectomy

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14
Q

Sertoli-leydig tumour of the ovary

  • Description
  • Bilateral?
  • Prognosis
A

Tumour of stromal origin
- Secreting hormones (androgens)

Rarely bilateral

Prognosis mainly good

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15
Q

Sertoli-leydig tumour of the ovary

- Presentation

A

Amenorrhea/ menstruation problems

Hair recession

Hirsutisim

Clitoromegaly

Acne

Voice deepening

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16
Q

Risk of malignancy index for ovarian tumours

A

Composed of

  • Menopause
  • USS scan
  • CA125 levels

> /= 250= referred

17
Q

Removal of ovaries in breast cancer

A

Removes source of oestrogen which promotes growth of breast cancer.

18
Q

Cyst

A

A closed hollow lesion, lined by epithelium

19
Q

Oestrogen secreting stromal tumour

A

Presents with post-menopausal bleeding

- Example: granulosa cell tumour

20
Q

Classification of ovarian tumours [5]

A

Tissue of origin
- Epithelial or stromal

Macroscopic appearance
- Cystic or solid

Content of the cyst
- Serous, mucin, dermoid

Histological

  • Benign
  • Borderline
  • Malignant

Number of cavities
- Multiocular or uniocular

21
Q

Draining of a cyst

A

Reduces the risk of bursting

Reduces the size- smaller surgical incision

22
Q

Resection of ovarian tumour

A

Must be intact

- Leakage of contents can put cancer cells into abdomen

23
Q

Borderline tumour features

A

Contains cellular features of cancer without invasion

Cystological atypia
- Varied nuclear size and shape

Nuclear stratification

Mitotic activity

Complex architecture

No invasion of the wall

24
Q

Ovarian tumour and haemorrhagic

A

Malignant tumours can erode their blood supply and cause bleeds
- Torsion increases pressure in capillaries

25
Q

Chocolate cysts

A

Blood collecting in cysts from endometriosis of the ovary