Ovarian Tumours Flashcards
Derived from a developing follicle
Follicular Cyst
Benign tumour derived from a corpus luteum that didn’t disintegrate
Corpus Luteum Cyst
Germ cell tumour of epithelial origin; benign
Dermoid cyst/teratoma
Epithelium benign tumour derived from columnar cells with cilia
Serous cystadenoma
On histology this ovarian tumour shows clustered epithelial cells
Brenner tumour (benign) - Called Walthard Cell Rests Other features include coffee bean nuclei a
This ovarian tumour is associated with Peutz-Jeugher
Serotoli-Leydig tumour (benign)
On histology this tumour has cells with coffee bean nuclei
Benign Brenner Tumour
Another feature: Walthard cells rests (Clusters of epithelial cells)
Benign Ovarian tumour associated with Meigs’ syndrome
Fibroma
Solid tumour consisting of bundles of spindle-shaped fibroblasts
Fibroma
Tumour occurring around menopause with a pulling sensation in the pelvis
Fibroma
Most common ovarian cancer
Serous cystadenocarcinoma
Psammoma bodies (collection of calcium) are seen
Serous Cystadenocarcinoma
Can be associated with pseudomyxoma peritonei
Mucinous cystadenocarcinoma
Most common malignant germ cell tumour
Dysgerminoma
Associated with Turner’s Syndrome
Dysgerminoma
Secretes AFP typically
Yolk Sac Malignant tumour
Malignant gestational trophoblastic disease, increased hCG
Choriocarcinoma
Oestrogen producing, malignant tumour
Granulosa cell tumour
Signet ring cell adenocarcinoma
Krukenberg tumour
Malignant tumour typically secretes hCG and LDH
Dysgerminoma
Schiller-Duval bodies on histology
Yolk-sac tumour malignant
Early haematogenous spread to the lungs
Choriocarcinoma
Presents as precocious puberty in children
Granulosa cell tumour
Metastasis from a GI tumour
Krukenberg tumour
Presents with endometrial hyperplasia in women
Granulosa cell tumour - malignant
Contains Call-Exner bodies (small eosinophilia fluid-filled spaces between granulosa cells)
Granulosa cell tumour
