Ovarian Carcinoma

Question 1

immature embryonal tissue

Answer 1

malignant teratoma - germ cell

Question 2

hobnail appearance

Answer 2

clear cell epithelial - MS1 mutation

Question 3

female counterpart of seminoma

Answer 3

dysgerminoma

Question 4

psammoma bodies

Answer 4

serous epithelial

Question 5

no psammoma bodies

Answer 5

mucinous epithelial

Question 6

secrete HCG

Answer 6

Choriocarcinoma germ cell. - trophoblastic tissue

Question 7

signet ring cells

Answer 7

secondary krukenburg tumour - from breast and gastric cancer

Question 8

secrete androgens

Answer 8

sertoli leydig cell - stromal/ sex cord - can be benign or malignant

Question 9

produce oestrogen

Answer 9

benign granulosa thecal cell tumour - stromal/sex cord

Question 10

stromal tissue fibroma

Answer 10

no hormone production - benign miegs syndrome 50%

Question 11

Miegs syndrome

Answer 11

triad of:
benign fibroma of stromal ovarian tissue
ascites
pleural effusion

Question 12

tubular glands

Answer 12

endometriod epithelial - CTNNB 1 mutation assocaited

Question 13

contains skin hair and teeth

Answer 13

dermoid cyst - benign mature terratoma - germ cell -benign but may transform to malignant.