Ovarian Cancer Flashcards
what lymph nodes drain the ovaries and testes
para-aortic
presentation of ovarian cancer
very vague - usually presents in advanced disease
tummy upset, early satiety, weight gain, loss of appetit, pelvic mass, bloating
what is stage 1 ovarian cancer and its cure rate
just in the ovaries - 85%
what is stage 2 ovarian cancer and its cure rate
ovaries with pelvic involvement - 47%
what is stage 3 ovarian cancer and its cure rate
in ovaries and has involvment outside pelvis and lymph nodes - 15%
what is stage 4 ovarian cancer and its cure rate
distant metastases - 10%
what blood test is raised in 80% of ovarian cancers
ca 125 - glyco-protein antigen
what benign states is CA-125 raised in
endometriosis, menstruation and PID
what is RMI
risk of maligancy index
factors used to calculate an RMI
Ultrasound features, Menopausal status and CA 125
what cancers is CA 125 raised in
ovary, colon, pancreas and breast
when is US used in ovarian cancer
in diagnosis and staging and to guide a biopsy
5 risk factors of ovarian cancer
HNPCC, BRAC1 or 2, early menarch, late menopause and nulliparity
who gets screened for ovarian cancer
women with 2+ relatives affects
HNPCC gene or BRAC1/2
true/false - some high risk women may recieve a prophylactic oophorectomy
true
