Outbreak Management Flashcards
1
Q
Disease Outbreak
A
- Increase to the total number or frequency of cases than would be expected at any given time and location
- Significant increase in severity or duration of clinical signs for any given disease
2
Q
Risk Factor Investigation
A
- Epidemiologic Triangle
- Pathogen
- Environment
- Host
3
Q
Pathogen
A
- Sucess of the pathogen will depend on several things
- Infectivity
- Suscepibility to treatments (Resiliency)
- Ability to survive outside the host
- Shedding
4
Q
Infectivity
A
- Amount of pathogen required to cause disease in a host
- Specific to each pathogen
- The lower infectivity, the lower the needed dose
- Can help judge an animal’s exposure risk
5
Q
Method of transmission
A
- Can help us determine exposure risk
- A pathogen that is spred through direct contact will generally expose a lower number of individuals
- Aerosol transmission will generally expose a higher number of individuals
6
Q
Host
A
- Several things contribute to the susceptibility of a host:
- Immunity (prior exposure)
- Response of the immune system
- Age
- Co-morbidities
- Vaccines can be protectve for the individual
- Animals with compromised immune system will be at higher risk
7
Q
Environment
A
- A Secure environment may depend on:
- Climate
- Physical barriers
- Population density
- Social structures
- Kennel Design (Substrates)
- For disease mitigation, a shelter will generally include a variety of small rooms to hold specific populations
- Kennel design- materials can contribute to disease prevention
- Ex: wood is porous and is considered an unacceptable substrate, since it has a high chance of holding pathogens
8
Q
Pathogen - Host Pathway
A
- Block by increasing the animal’s ability to fight of disease
- Vaccination
- ID and treat
- Nutrition

9
Q
Host - Environment Pathway
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- Boost immunity through comfort
- Primary enclosures
- Maintain capacity
- Plan animal/people traffic flow

10
Q
Environment - Pathogen Pathway
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- Decrease the chance of encountering a pathogen
- Disease transmission
- Sanitation
- Design
11
Q
Management Strategies
A
- Shelters will never be able to eliminate all diseases entering, but can limit the disease impact
- Management Strategies include:
- Prevention- Shelter rounds, vaccination, capacity maintenance, cleaning
- Diagnosis- ELISA, PCR
- Isolation
- Quarentined
- Decontamination
- Clean break
- Shelters are always implementing at least 1, but may do several during an outbreak
12
Q
Prevention:
A
- Shelter Rounds: one of the most important
- Observe each animal every day, checking for medical or behavioral changes in the individuals and trends in the population
- Monitor that recommended protocols are being implemented
- if protocols are successful at breaking one side of the epidemiologic triangle, disease will not occur.
13
Q
Protocols:
A
- May include:
- vaccination at time of intake
- limiting crowding to improve animals well-being within the environement
- Giving broad-spectrum cleaning and disinfection
- Protocols for specific diseases may not be used daily, should be easily accessible for outbreaks
- Diseases should have protocols addressing:
- clinical signs
- severity of illness
- affected species ans zoonotic potential
- mode and ease of transmission
- incubation period
- shedding interval (pre- and post-infection)
- carrier state
- pathogen longevity in environment
- effective disinfection strategies
- reliability of screening and Dx tests
- preventation tools (vaccination)
- identigy at-risks groups,
- recovery time
14
Q
Data collection
A
- Imperative prior to and throughout an outbreak
- Should anser the questions:
- Who is affected - signalment
- What control measures have been implemented
- When did clinical signs start
- Where did affected animals com from and where are they in the shelter
- Why is this happening - diagnosis
- How many affected
15
Q
Diagnosis
A
- Diagnosis of the pathogen causing the outbreak is a necessary component of outbreak management
- Even is the diagnosis is obvious, verification is imperative
- Identification of pathogen, reveals important characteristics and can be used to end the outbreak
- Shedding
- Incubation
- Transmission
- Longevity in environment
- Effectiveness of disinfectants
- Effectiveness of vaccination
- Tests with rapid results are preferred
- ELISA vs. PCR
- Test all necessary animals
- symptomatic
- highlyy suspicious exposure history
16
Q
ELISA (Enzyme-linked immunosorbent assay) tests
A
- Point-of-care, rapid, easy-to-use tools that can test for proteins assoiated with specific pathogens
- Commonly utilized in a shelter setting to evaluate for diseases such as:
- Parvo
- Feline Immunodeficiency virus (FIV)
- Feline Leukemia Virus (FeLV)
- Heartworm
- Considered less sensitive than PCR test
17
Q
Polymerase Chain Reaction (PCR) tests
A
- Detect a specific sequence of DNA or RNA within a pathogen in order to identify the presence o a pathogen, making it extremely sensitive
- Can be utilized in a comprehensive manner
- Ex: Feline/Canine Respiratory PCR panel can test for all common pathogens that may be contributing to clinical signs of an upper respiratory infection
- Advantage of being able to quantitate results
- Ex: a dog that has been vaccinated for distemper virus may have a positive PCR test, but the amount of pathogen detected should be considerably less in a vaccinated dog versus a dog with an active infection
- Drawback is that it can take several days for available results (critical time with an active oubreak)
18
Q
Testing
A
- Testing every animal would be excessive, expensve, and unproductive
- Target animals
- who are symptomatic (ideally, 10-30%)
- those that are considered high risk for exposure
19
Q
Isolation
A
- “Separation for clinically ill animals with a communicable disease from the rest of the shelter
- Isolating sick animals is the single most important step of outbreak management
- achieves physical containment of the pathogen
- reduces transmission of disease
- decreases the infectious dose throughout the shelter
- If fast/reliable diagnostic test is not available animals may need to be placed in isolation soley on suspicious clinial signs
- On-site areas are physically separated from other animal housing
- Alternative options can be explored
- transfer to another clinic, vet facility, or foster
- Alternative options can be explored
- Animals will be isolated for the length of the contagious period
- Results in longer length of stay
- Will contribute to a significant drain on the shelters resources
- Results in longer length of stay
- Euthansia may be considerd of clinically sick animals during an outbreak
20
Q
Quarantined
A
- Animals kept in a separate housing area to see if they become ill in order to limit exposure to the healthy population
- There are several reasons an exposed animal may not be displaying clinical signs:
- incubation period
- subclinical infection
- animmune
- not exposed
- There are several reasons an exposed animal may not be displaying clinical signs:
- Quarantine area should have designated PPE, cleaning supplies, and disinfection supplies
- Animals can be individually assessed for risk through diagnostic testing.
- Serologic testing can check for protective antibody titers.
- Animals that show no clinical signs and is proven to have protective amounts of antibodies, is low risk and can be moved out of quarantine.
- ELISA or PCR can be used to check for the pathogen within the animal
- Positive tests will cause the animal to be moved to isolation
- If testing can’t be performed animals will remain in quarantine for the length of the incubation period
- Serologic testing can check for protective antibody titers.
- When animals become clinically infected, individual animals should be immediately moved to isolation
- At hat point, all animals in quarantine are considered newly exposed and the incubation is reset for the quarantine area
21
Q
Decontamination
A
- All areas within the shelter, all sorces of environmental contamination should be investigated and decontaminated
- Potential contanimates come from:
- animal hair
- equipment
- crates/carriers
- clothing
- common/administration space
- vehicles
- toys
- Effective agents will depend on the pathogen
- Carpet and unsealed wood cannot be disinfected and should be disposed of
22
Q
Adoption
A
- During outbreak conditions, it may be best to stop all intake and adoption activities until disease transmission has been resolved
- Possible for some limited admission shelters, but open admission shelters cannot always stop intake
- Especially if for strays in imminent danger, dangerous animals, and cruelty cases
- Alternatives: Diverting intake to other shelters, using a temporary annex facility, or allowing adoptions straight from foster homes/off site events
- Or implement a “clean break” strategy
23
Q
Clean Break
A
- Strategy to protect the new population from being introduced
- Animals are separated as far away as possible from those that are infected and exposed
- The clean area should be treated as a “good isolation” area utiliting strict biosecurity protocols to include its own PPE, cleaning supplies, and disinfecting agents
- signage may help define the clean area and decrease the chances of cross-contamination
- Vaccination and prophylactic care should be provided to new animals
24
Q
Impact of Disease outbreak
A
- Outbreak can have numerous consequences such as:
- euthanasia of adoptable animals
- Deceased adoptions
- Financial burdens
- resource allocation
- low staff morale
- tarnished repuation
- vicious cycle of overcrowding
- All leading to a general decrease in life saving capacity
- Damages can be somewhat mitigated through examplary communication standards
- Proactive communication averts spread of rumors and false information, improves the shelter’s image, and enlists public support and trust
- Communication starts within the shelter staff, but should also include community stakeholders (volunteers, donors, adoptors, etc.)
- Disseminating accurate information will noot be the sole responsibility of the veterinarian in charge, though the vet will play a crucial role
- Communication is a group effort
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