OTO-Logic Flashcards
Aspirin-desensitization therapy has been shown to increase the ___ between revision surgery, or in some patients, to prevent ___ recurrence.
Aspirin-desensitization therapy has been shown to increase the Time Interval between revision surgery, or in some patients, to prevent Polyp recurrence.
Aspirin-desensitization therapy should ideally be started ____ weeks after sinus surgery.
3-4 weeks after sinus surgery.
Continued ___ dosing is required to maintain desensitization following Aspirin-desensitization therapy.
Daily dosing
In patients with olfactory loss w/out visible evidence of sinonasal inflammation on endoscopy, what is appropriate counseling regarding therapeutic options?
“The addition of ___ ___ to olfactory training has shown improved recovery of olfaction compared to saline irrigation alone.”
The addition of Budesonide Irrigations to olfactory training has shown improved recovery of olfaction compared to saline irrigation alone.
___ and ___ is associated with a lower degree of improvement in SNOT-22 scores following ESS.
Tobacco use and Increased length of f/u.
A 28-year-old man from Sudan presents with nasal obstruction secondary to a 9 year history of painless nasal mass (CT shown below). Biopsy of the left nasal mass shows histiocytes with “foamy, moth-eaten” cytoplasm with epithelioid cells. Silver stain showed intracellular bacilli. What is the most likely diagnosis?
Rhinoscleroma.
(Rhinoscleroma is caused by infection with Klebsiella rhinoscleromatis. Sporadic cases have been reported in the United States, but the disease is endemic in Central and South America, Africa, the Middle East, and parts of Asia. Disease progression moves through exudative, granulomatous, and sclerotic phases. The pathologic appearance described here is characteristic of the granulomatous phase.)
What is the most common side effect of Dupixent (Dupilumab) experienced by patients on this medication?
- Nasopharyngitis/worsening or persistence of nasal polyps
- Worsening Asthma
- Injection site erythema
(In order of prevalence)
Dupixent is an anti ___ monoclonal antibody (mAb) that inhibits the production of IL-4 and IL-13.
Dupixent is an anti IL-4R(alpha) monoclonal antibody (mAb) that inhibits the production of IL-4 and IL-13.
Dupixent is an anti IL-4R(alpha) monoclonal antibody (mAb) that inhibits the production of ___ and ___.
Dupixent is an anti IL-4R(alpha) monoclonal antibody (mAb) that inhibits the production of IL-4 and IL-13.
A 69-year-old female presents with nasal obstruction, facial pressure and discolored nasal drainage for 4 months that is recalcitrant to topical steroid sprays, nasal irrigations, and oral antibiotics.
Diagnosis?
Inverted papilloma with a bony stalk attaching near the infraorbital nerve
A 69-year-old female presents with nasal obstruction, facial pressure and discolored nasal drainage for 4 months that is recalcitrant to topical steroid sprays, nasal irrigations, and oral antibiotics.
What next step would assist in diagnosis?
A biopsy is warranted to confirm the diagnosis, w/use of a bioendoscopy filter.
CT of paranasal sinuses reveals erosion or expansion into
lateral nasal wall or extension into maxillary or ethmoid sinuses, and may reveal calcifications.
Diagnosis?
Inverted Papilloma.
CT/CTA/MRI/MRA of paranasal sinuses, shows a mass with extension into the pterygomaxillary fissure.
Dx?
JNA
“Double density sign” on CT sinus scan
Fungal sinusitis.
“Signal dropout of T2-weighted MRI” on CT sinus scan
Fungal sinusitis.
