BoardVitals Flashcards
55yo M with a painless mass in his nose. Biopsy shows “foamy histiocytes,” w/a “moth-eaten” cytoplasm and large plasma cells w/birefringent inclusions. Most likely diagnosis?
Rhinoscleroma
Rhinoscleroma is caused by ___.
Klebsiella Rhinoscleromatis.
Foamy histiocytes (vacuoled macrophages) of Rhinoscleroma are called ___.
Mikulicz cells
Bloated plasma cells of Rhinoscleroma are referred to as ___.
Russell bodies
A ___ presents in teenage males and histopath shows numerous thin-walled vessels, bland epithelium, and fibrous stroma that become fibrotic and less vascular with maturity.
JNA
A JNA presents in teenage males and histopath showing numerous ___(1)___, ___(2)___, and ___(3)___ that become fibrotic and less vascular with maturity.
(1) thin-walled vessels
(2) bland epithelium
(3) fibrous stroma
Churg Strauss syndrome is a small vessel vasculitis that causes _____.
angiitis and allergic granulomatosis
___ is a small vessel vasculitis is that causes angiitis and allergic granulomatosis.
Churg Strauss syndrome
What is true regarding the use of an image guidance system during endoscopic sinus surgery?
The AAOHNS endorses the use of image guidance systems for disease abutting the skull base.
An 85yo M for recurrent expistaxis and nasal congestion. On PE, a pigmented lesion is seen in the R NC. A biopsy frozen section shows small round blue cells. The final path report shows: HMB 45 (+), Cytokeratine (-), Neuron specific enclose (-), S-100 (+), Deamin (-). What is the likely diagnosis?
Melanoma
Also typically melan-A positive
Which sinonasal tumor is: HMB 45 (-), Cytokeratine (+), Neuron specific enclose (+), S-100 (-), Deamin (-)
Sinonasal undifferentiated carcinoma
Which sinonasal tumor is: HMB 45 (-), Cytokeratine (-), Neuron specific enclose (+), S-100 (-), Deamin (-)
Ewing Sarcoma
Which sinonasal tumor is: HMB 45 (-), Cytokeratine (-), Neuron specific enclose (-), S-100 (-), Desmin (+)
Rhabdomyosarcoma
Which Two sinonasal tumors are Neuron specific enolase (+)
- Ewing Sarcoma
- Esthesioneuroblastoma
Due to normal anatomical variance, the Frontal Sinus will drain ___ to the uncinate and into the ___ in approximately 20% of people
Lateral to the uncinate and into the infindibulum
In 20% of patients the uncinate attaches to the ___.
Skull base or Middle turbinate.
In 20% of patients the uncinate attaches to the skull base or middle turbinate, causing the frontal sinus to drain:
Directly into the ethmoid infindibulum.
In 80% of people, the uncinate process attaches to the ____.
Lamina papyracea
The uncinate attaches to the lamina papyracea in 80% of cases and drainage from the frontal sinus is
Medial to the uncinate and into the infindibulum.
A 49yo M undergoes endoscopic sinus surgery for isolated sphenoid sinusitis. A wide b/l sphenoid osteotomy is performed and the sinus is debrided. A pulsation is visible along the L lateral wall at which point a bony dehiscence over the ___ is noted.
Carotid artery
A 49yo M undergoes endoscopic sinus surgery for isolated sphenoid sinusitis. A wide b/l sphenoid osteotomy is performed and the sinus is debrided. A pulsation is visible along the L lateral wall at which point a bony dehiscence over the carotid artery is noted. What segment of the carotid artery is this?
Cavernous segment - 5 segments within the cavernous sinus as it makes two turns
7 segments of the ICA
“C’mon Please Learn Carotid Clinical Organizing Classification”
C: cervical segment P: petrous segment L: lacerum segment C: cavernous segment C: clinoid segment O: ophthalmic segment C: communicating segment
What is the most common cause of anosmia?
Obstructive and inflammatory nasal disease
A 25yo M presents with painful inflamed folliculitis on the nasal tip. What nerve transmits pain from this region?
External nasal branch of anterior ethmoidal nerve (branch of V1)
A 20yo M presents w/a 7mo h/o unilateral nasal obstruction, change in voice pitch, and R-sided sinus pressure. CT w/o con reveals a mass filling the posterior R nasal cavity extending posteriorly into the nasopharynx. Endoscopic exam reveals a bluish vascular smooth mass in the R nasal cavity. What is the next appropriate diagnostic study to delineate the extent of the mass into the infra-temporal space?
MRI w/con
A 20yo M presents w/a 7mo h/o unilateral nasal obstruction, change in voice pitch, and R-sided sinus pressure. CT w/o con reveals a mass filling the posterior R nasal cavity extending posteriorly into the nasopharynx. Endoscopic exam reveals a bluish vascular smooth mass in the R nasal cavity. What is the preferred initial study for this mass?
CT w/con (this is most likely a JNA
A 20yo M presents w/a 7mo h/o unilateral nasal obstruction, change in voice pitch, and R-sided sinus pressure. CT w/o con reveals a mass filling the posterior R nasal cavity extending posteriorly into the nasopharynx. Endoscopic exam reveals a bluish vascular smooth mass in the R nasal cavity. What is the diagnosis?
JNA
A 20yo M presents w/a 7mo h/o unilateral nasal obstruction, change in voice pitch, and R-sided sinus pressure. CT w/o con reveals a mass filling the posterior R nasal cavity extending posteriorly into the nasopharynx. Endoscopic exam reveals a bluish vascular smooth mass in the R nasal cavity. The diagnosis of JNA is made. What study should be performed w/in 24hrs of surgical excision?
Angiography - to embolize the tumor and decrease intraoperative blood loss
Which neurotransmitter acts to dilate the nasal microvasculature?
Acetylcholine
What is represented by the asterisk, according to the Kuhn classification?
Type IV Kuhn Cell
What is the Kuhn classification?
This describes 4 pneumatization patterns of the frontal sinus, and recess cells
What is Type 1 of the Kuhn classification of fronto-ethmoidal cells
A single cell superior to the agger nasi.
What is Type II of the Kuhn classification of fronto-ethmoidal cells
A tier of 2 or more cells above the agger nasi cell. (The asterisk indicates an Agger nasi cell)
What is Type III of the Kuhn classification of fronto-ethmoidal cells
A single cell extending from the Agger cell into the frontal sinus (the * indicates an Agger nasi cell)
What is Type IV of the Kuhn classification of fronto-ethmoidal cells
An isolated cell within the frontal sinus
A 48yo M with a history of chronic nasal obstruction presents with concern for persistent septal deviation, despite prior septoplasty. On exam, he is noted to have a R septal deflection and a spur of the maxillary crest region obstructing the R nasal floor. Advantages of an endoscopic vs. traditional extracorporeal approach include all of the following except:
A. Improved visualization of the posterior bony septum
B. Ability to perform incision posterior lumbar
C. Decreased rate of septal perforations
D. Excellent teaching tool
Decreased rate of septal perforations.
The distance of the anterior lacrimal crest to the anterior ethmoid artery is ___mm.
24mm
The distance of the anterior ethmoid artery to the posterior ethmoid artery is ___mm.
12 mm
The distance of the posterior ethmoid artery to the optic canal is ___mm.
6mm
A 30yo F from Kentucky is found to have findings on CT scan suspicious of allergic fungal sinusitis. What RF is most closely associated with allergic fungal sinusitis?
A history of atopy (eg, asthma). This is thought to be an allergic response to a fungal antigen.
A 25yo F who is 10 weeks pregnant presents with complaints of clear rhinorrhea and nasal congestion for the last 2 weeks. After a thorough hx and nasal endoscopy, a dx of rhinitis of pregnancy is made. She is interested in a topical nasal spray, but is concerned about side effects and harm to fetus. What intranasal corticosteroid sprays have been shown to cause congenital malformations.
Triamcinolone (associated with congenital respiratory tract defects)
A 72yo presents for eval of anosmia. His UPSIT (Smell Identification Test) reveals a score of 14. Endoscopic exam reveals no evidence of sinonasal pathology. He denies any trauma and reportedly, his outside MRI is unremarkable. What physical exam finding may elucidate the cause of this patient’s symptoms?
Most causes of hyposmia and anosmia in the older populations are idiopathic in nature, however, if bulbar symptoms or motor exam findings are noted, a diagnosis of Parkinson’s or other neurodegenerative condition must be excluded.
A patient with an esthesioneuroblastoma presents for Tx. Her tumor involves the nasal cavity and paranasal sinuses, with extension beyond the paranasal sinuses, but no evidence of distant mets or involvement of the regional LNs. What Kadish group does she fall in?
Kadish Group C (tumor extends beyond the nasal cavity and paranasal sinuses (skull base, intracranial compartment, orbit, or cribiform).
What is Kadish Group A?
Staging of sinonasal and ventral skull base malignancies.
A: tumor limited to the nasal cavity
Kadish Group B
Staging of sinonasal and ventral skull base malignancies.
B: tumor limited to the nasal cavity and paranasal sinuses
What is Kadish Group C?
Staging of sinonasal and ventral skull base malignancies.
C: tumor extends beyond the nasal cavity and paranasal sinuses (base of skull, intracranial compartment, orbit, or cribiform).
What is Kadish Group D?
Staging of sinonasal and ventral skull base malignancies.
D: cervical nodal or distant metastases
Fill in the blank.
Anterior septal branch of the Anterior Ethmoidal Artery
Fill in the blank.
Septal branch of the Posterior ethmoidal a.
Fill in the blank.
Posterior septal branch of sphenopalatine a.
Fill in the blank.
Greater palatine artery
Fill in the blank.
Nasal septal branch of superior labial branch of facial a.
A 38yo F is referred for 2 weeks of rhinorrhea. She indicates it is almost exclusively R-sided and persistent. When she goes to the bathroom, the rate of rhinorrhea increases. She denies any recent head trauma. She denies a h/o allergies. Given her likely diagnosis, what would be the blood supply for the septal flap which could be useful in treating her?
Posterior septal branches of the Sphenopalatine a.
A 38yo F is referred for 2 weeks of rhinorrhea. She indicates it is almost exclusively R-sided and persistent. When she goes to the bathroom, the rate of rhinorrhea increases. She denies any recent head trauma. She denies a h/o allergies. What is her most likely diagnosis?
Spontaneous CSF leak
Endoscopic exam reveals a pale, polyploid lesion emanating from the middle meatus, obstructing the view of the middle turbinate. Biopsy of the mass is concerning for an ___.
Inverted Papilloma
From which sinonasal site does an inverted papilloma most frequently arise?
Lateral Nasal wall (in the fontanelle area)
Which sinus is the most commonly affected sinus by an inverted papilloma?
Maxillary sinus
Which of the following arteries does NOT contribute to the vascular plexus on the anterior nasal septum?
A. Ophthalmic B. Facial C. Descending palatine D. Maxillary E. Lesser palatine
E. Lesser palatine
A CT scan is performed on a 52yo F. What symptom most likely prompted this CT scan, showing this benign, osteogenic tumor?
This patient has an osteoma of the ethmoid sinuses. While many are found incidentally on CT scans of the brain, face, or orbits, when a symptom prompts ordering the scan, it is most commonly a HEADACHE.
The opthalmic division of the trigeminal nerve (CN V1) divides into 3 main branches: ___.
Frontal n., Lacrimal n., and Nasociliary n.
Which nerve(s) gives rise to branches that provide sensory innervation to the medial alae of the nose?
The nasociliary branch of the opthalmic n. (V1) innervates the ciliary body, iris, cornea, and conjunctiva. It’s terminal branch is the Anterior Ethmoidal n., which innervates the medial nasal alae via the external nasal n.
Any patient presenting with an osteoma of the sinuses should be evaluated for ___.
Gardener’s syndrome (affects 10% of individuals with familial adenomatous polyposis (FAP).
Gardener’s syndrome is associated with ___, ___, and ___.
- Osteomas of the head & neck
- Adenomatous polyposis
- Supernumerary teeth
The survival rate for invasive fungal sinusitis in a DKA patient is up to ___ in diabetic patients b/c DKA is reversible. The survival rate is less than ___ in non-diagnostic patients.
Diabetic - 80%
Non-Diabetic - <50%
A sinus infection from which bacterial organism is most likely to resolve without antibiotics?
Moraxella catarrhalis
Chandler’s classic action I
Preseptal cellulitis (edema of the preseptal tissues and NO ocular involvement)
Chandler’s Classification II
Orbital Cellulitis:
- chemosis (swelling of bulbar conjunctiva)
- EOM impairment
- possible visual impairment
Chandler’s Classification III
Subperiosteal abscess:
- worsening chemosis (swelling of bulbar conjunctiva
- exopthalmos
- EOM and visual impairment
What are the boundaries of the frontal recess?
Anterior: agger nasi,
Posterior: ethmoid bulla + basal lamella
Lateral: middle turb
Medial: lamina paprecia
A 35 M presents w/recurrent nosebleeds and is found to have palatal lesions seen in image.
- Dx?
- Associated finding?
- Hereditary hemorrhagic telangiectasia
- Pulmonary AV malformation
In what percent of patients is the carotid a dehiscent in the sphenoid sinus?
21-30% (specifically, 23%).