OTHER TYPE OR THYROID DISORDER

Question 1

• Caused by Bacterial Infection notable from Gram Positive Staphylococcus aureus.
• Bacterial ID is done through FNAC for high yield
  Individual with this condition have history of pre-existing nodular (COLD NODULES) goiter with neck pain

Answer 1

Suppurative Thyroiditis or
Microbial Inflammatory Thyroiditis

Question 2

• Commonly observed in hospitalized patient
• Characterized by reversible alteration of HPTA
• Markedly Decrease T3

Answer 2

Euthyroid Sick Syndrome / Nonthyroidal Illness Syndrome

Question 3

• Formerly known as Thyroid Hormone Resistance Syndrome
• Due to mutations in one of the T3 beta receptor leading to low cellular binding of T3
• Decreased tissue sensitivity to thyroid hormone caused by the germline mutation
• Mutant receptor has lower binding affinity
• TSH level remains unsuppressed despite elevated thyroid hormone
• Mutation of THRB Gene located in CHROMOSOME 3

Answer 3

Syndrome of Impaired Sensitivity to Thyroid Hormone