Other Stuff Flashcards

1
Q

5HT2 agonist

A

LSD

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2
Q

5HT1A agonist

A

Buspirone

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3
Q

5HT1D agonist

A

Sumatriptan

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4
Q

SSRI

A

Fluoxetine

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5
Q

MAOI

A

Phenelzine

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6
Q

5HT2 antagonist

A

Cyproheptadine

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7
Q

5HT3 antagonist(s)

A

Ondansetron

Alosetron

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8
Q

1st generation H1 blockers

A

Diphenhydramine
Dimenhydrinate
Promethazine
Chlorpheniramine

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9
Q

2nd generation H1 blockers

A

Loratidine
Desloratidine
Ceterizine
Fexofenadine

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10
Q

H2 blockers

A

Cimetidine
Ranitidine
Famotidine

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11
Q

PGE1 analog(s)

A

Misoprostol

Aloprostadil

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12
Q

PGE2 analog

A

Dinoprostone

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13
Q

PGE1(2) analog

A

Epoprostenol

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14
Q

PGF2 analog

A

Carboprost

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15
Q

PGF2(alpha) analog

A

Bimatoprost

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16
Q

Eicosanoid function – Platelets
TXA2
PGI2

A

TXA2 - promotes platelet aggregation

PGI2 - inhibits platelet aggregation

17
Q

Eicosanoid function – Repro and Parturition
PGI2
PGE2
PGF2

A

PGI2 - Relaxation of uterine tone
PGE2 - initiation and progression of labor (uterine contractility and cervical ripening)
PGF2 - uterine contractility during labor, primary dysmenorrhea

18
Q

Eicosanoid function – CV & Vasculature
PGE2, PGI2, PGD2
TXA2, PGF2, PGD2 (pulmonary only)

A

PGE2, PGI2, PGD2 - vasodilators

TXA2, PGF2, PGD2 - vasoconstrictors

19
Q

Eicosanoid function –Development

PGE2

A

PGE2 - maintains ductus arteriosus

20
Q

Eicosanoid function – Pulmonary smooth muscle
PGEs, PGI2
TXA2, PGF2, PGD2, LTC4, LTD4

A

PGEs, PGI2 - Relaxation

TXA2, PGF2, PGD2, LTC4, LTD4 - Constriction

21
Q

Eicosanoid function – Kidney

PGE2, PGI2

A

PGE2, PGI2 - Increase RBF due to vasodilation

22
Q

Eicosanoid function –Gastrointestinal
PGE2, PGI2
PGE2

A

PGE2, PGI2 - inhibits gastric acid secretion, increase gastric mucosal blood flow
PGE2 - viscous mucus secretion, bicarbonate secretion, contraction of GI smooth muscle

23
Q
Eicosanoid function -- Inflammation 
PGE2
PGE2, PGI2
LTC4, LTD4
LTB4
A

PGE2 - fever
PGE2, PGI2 - Pain, sensitize afferent nerve ending by lowering nociceptor threshold
LTC4, LTD4 - Vasoactive effects, increase vascular permeability
LTB4 - Neutrophil chemotaxis