Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Immunology > Other Exam 1 Questions > Flashcards

Other Exam 1 Questions Flashcards

1
Q 
Which of the following is NOT a potential consequence of acute inflammation
A. Resolution
B. Autoinflammation
C. Scarring
D. Chronic inflammation
E. Abscess formation
A

B. Autoinflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q 
A three-year-old male presents with increased susceptibility to infection with Neisseria meningitidis.  Which of the following complement components/regulators is he most likely missing?
A. C1
B. C1 inhibitor
C. DAF
D. C4
E. C5
A

E. C5

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q 
Identify the PAMP from the list below
A. C5a
B. TGFβ
C. TLR4
D. LPS
E. CD31
A

D. LPS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q 
One of the consequences of TLR ligation is
A. Activation of NFκB
B. Phagocytosis
C. Inhibition of IRFs
D. Caspase-1 activation
E. IL-1 production
A

A. Activation of NFκB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q 
Which of the following is most important for host defense?
A. NADPH oxidase
B. Epithelial barrier function
C. Phagocytosis
D. TNF production
E. Interferon production
A

B. Epithelial barrier function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Natural Killer cell mediated ADCC requires
A. Antibody binding to bacteria
B. Antibody binding to host cell
C. Antibody binding to a virus
D. Antibody that does not bind to a target

A

B. Antibody binding to host cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The three main effector functions of complement are
A. Opsonization, leukocyte migration, pathogen lysis
B. Phagocytosis, leukocyte migration, pathogen lysis
C. Opsonization, leukocyte activation, pathogen lysis
D. Phagocytosis, leukocyte activation, pathogen lysis

A

A. Opsonization, leukocyte migration, pathogen lysis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which of the following pathogen surfaces would NOT be amenable to triggering complement activation?
A. A pathogen that is opsonized with IgG
B. A pathogen that is opsonized with IgM
C. A pathogen that is expressing mannose
D. A non-opsonized pathogen
E. All of the above are amenable to complement activation

A

E. All of the above are amenable to complement activation

?

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q 
Which of the following enzyme complexes is directly responsible for generation of the most potent complement anaphylatoxin?
A. C1 convertase
B. C3 convertase
C. C5 convertase
D. Membrane attack complex
E. C1 inhibitor
A

B. C5 convertase. C5a is the most potent complement anaphylatoxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q 
Which of the following cytokines would most likely be the most effective anti-viral therapy?
A. TNF
B. IL1
C. IL6
D. IFNγ
E. IFNα
A

E. IFN-alpha

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q 
Which of the following is NOT a cardinal sign of inflammation?
A. Pus
B. Redness
C. Swelling
D. Heat
E. Pain
A

A. Pus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q 
Which of the following inflammatory mediators directly promotes vasodilation and vascular permeability?
A. TNF
B. IL1
C. Histamine
D. C5a
E. Bradykinin
A

C. Histamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q 
Hageman factor is activated by which of the following?
A. Microbial surfaces
B. Epithelium
C. Endothelium
D. Basement membrane
E. Histamine
A

D. Basement membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q 
PMN tethering (aka rolling) to endothelium is mediated by which pair of receptors?
A. Chemokines and chemokine receptors
B. Integrins and integrin ligands
C. Selectins and selectin ligands
D. PECAM:PECAM
A

C. Selectins and selectin ligands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q 
P-selectin is stored in which intracellular compartment?
A. Mast cell granule
B. PMN granule
C. Endothelial Weibel-Palade bodies
D. Monocyte/macrophage endosome
E. Epithelial body
A

C. Endothelial Weibel-Palade bodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q 
Which of the following cytokines is most likely to be involved in tissue repair and resolution of inflammation?
A. IFNγ
B. TNF
C. IL-1
D. IL-6
E. TGFβ
A

E. TGF-beta

Immunology (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions