Other endocrine lecture Flashcards
Diabetes
Type I
body doesn’t make enough insulin
DB T2
- body’s cells can’t let the insulin in to use it
Vessels are supersaturated with glucose
what happens as a result of DB
Glucose builds up in the blood stream (hyperglycemia)
and causes damage –
Blood vessels (plumbing) are full of sugar but your body is in a state of starvation.
Diabetes Mellitus
Presentation/Symptoms:
- urinating often (bc so much glucose)
- –> makes you v thirst and tired
- blurry vision
- Cuts/bruises slow to heal
- tingling pain in hands and feet
- feeling v hungry even tho eating
- weight. loss even tho eating more
How do you diagnosis DM
- fasting plasma glucose >126mg/dl
- A1C levels are >6.5%
- random plasma glucose >200 mg/dl
- A1C >5.7 -> impaired glucose tolerance
- 75g two hours oral glucose tolerance test with plasma glucose >200mg/dL
Diabetes Mellitus
Sequelae/consequences:
- frequent infections (UTI, yeast)
- Retinopathy -> blindness
- Nephropathy -> kidney. failure
- Neuopathy. of feet. a nd hands
- increase in CV events. (MI, strokes), peripheral vascular dz, poor healing wounds
DM: Type 1 Age of onset: Body type: Mechanism: DKA: Clinical sx: Monitor: Target. A1C: Tx:
childhood, adolesence thin or normal Pancreas can't make insulin d/t autoimmune Yes DKA Polydipia, polyuria, nocturia Monitor B.S and HbA1C <7.5 Insulin
Type 2 Age of onset: Body type: Mechanism: DKA: Clinical sx: Monitor: Target. A1C: Tx:
adults, but young kids who are obsese obese impaired insulin secretion, increase resistance No DKA polydipsia, polyuria and nocturia B.S and Hb1AC <7 modify lifestyle, oral DM meds, insulin
sx of db
- Acanthosis nigracans- dark skin often on neck
- DB retinopathy
- DB neuropathy- ulcers on feet
4.
Test for DB neuropathy
- Check for skin lesions/ infection, etc (don’t forget to
check between the toes - Pressure sensation using Monofilament testing (6 spots- 1 on big toe, pinky toe, 3 on upper feet, 1 on heel)
- Vibration sensation using tuning fork
- Superficial pain using pinprick/ temperature
sensation - Reflexes
- Pulses
Diabetic Peripheral neuropathy
affects 30%. of DB its d/t damaged peripheral nerves d/t poor controlled blood sugar
stocking. and glove pattern: usually. appears on feet and arms
burning, paresthesia, numbness
infections, amputations
tx Diabetic Peripheral neuropathy
control b.s
A1C <6.5
perform self foot exam routinely
anti neuropathy meds
how do document DB foot exam
No lesions, callus on examination of feet, toes, between toes
– Dorsalis pedis pulse +2
– Vibratory sense intact bilaterally
– decrease sensation to monofilament in left lateral foot, right
great toe vs Sensation intact to monofilament.
Metabolic Syndrome
• Also known as
syndrome x
insulin resistance syndrome
Metabolic Syndrome consists of
- abdominal obesity
- insulin resistance
- high BP
- high TAG levels (lipid abnormalities)
Metabolic Syndrome prevalence increases with what?
age
increasing body weight
causes of Metabolic Syndrome
idk
but most. likely. linked to:
- visceral fat causing oxidative stress that produces endothelial cell dysfunction, promoting vascular damage
and atheroma formation - hormonal changes that causes serum cortisol to increase -> abdominal obesity, insulin
resistance, and lipid abnormalities
work up of metabolic syndrome
- Good past medical and family history (specifically
hx of cardiac disease or DM) - History of weight changes
- Lifestyle (i.e. sedentary, eating habits)**
what should we note about metabolic syndrome
- in some patients, certain meds can increase risk of MS: antipsychotics, antivirals, steriods
- Certain med conditions can increase risk: PCOS
tx MS
excercise
diet
treat HTN
Treat cholesterol (bc patients. will have low HDL cholesterol_
- Understand who needs a geriatric assessment
a
Understand how to assess the medications a geriatric patient is taking and how to use specific
tools/ criteria to help safely prescribe medication to a geriatric patient
a
Understand the assessment tools that need to be used for functional ability and risk of falls
a
Know some of the common pathology for vision impairment in the geriatric population and when
to refer to ophthalmology
a
- Have general understanding of how to assess cognitive decline
a