Other Drugs Flashcards
Daliresp
Roflumilast Diarrhea, psychiatric/ suicide, wt loss, insomnia, HA PDE-4 inhibitor Tablet COPD Must use with laba Medguide Liver
Patiromer indication
Hyperkalemka
Veltassa
Patiromer
Grisofulvin
Dernatomycosis and tinea infections of hair, skin, and nail
- liver, photosensitivity, pregnancy
- increases metabolism of BC
Take with fatty meal
Terbinafine tox
Hepatotoxicity
-2D6 inhibitor
Xofluza
Baloxavir
Flu
Single dose regimen
Start within 48 h
Amantadine for flu
Influenza A
Rimandtidine
Flumadine
Flu
Zovirax
Acyclovir
Sitavig
Acyclovir
Denavir
Penciclovir
Probenecid
Urocosuric for gout
sulfa alergy
Nasacort
Trimancinolone nasal spray
Beclonase
Beclomethasone
Nasal ICS
Omnaris, zetonna
Ciclesonide
Nasal ICS
Diphenhydramine
Gen 1
Clemastine
Gen 1antihistamine
Carbinoxamine
Gen 1 antihistamine
Karbinol
Chlorpheniramine
Gen 1 antihistamine
Azelastine
Intranasal antihistamine
Patanase
Olopatadine
Intranasal antihistamine
Xyzal
Levocetirizine
CI: ESRD
Afrin
Oxymetazoline
Nasal decongestant
Max 3 days
Tetrahydrozoline
Intranasal decongestant
Cromolyn
Nasalcrom
Mast cell stabilizer for allergic rhinitis tx and ppx
SCh not PRN
Intranasal ipratropium bromide
Rhinorrhea
Guafenacin brand names
Robafen, mucinex, robitussin
Xelpros
Latanoprost without BAK
Carbachol
Cholinergic eye drop
Pilocarpine
Cholinergic eye drop
Simbrinza
Brinzolamide + brimonidine
Trusopt
Dorzolamide
Carbonic anhydride inhibitor
Azopt
Brinzolamide
Alphagan P
Brimonidine
Alpha 2 agonist
Combigan
Timolol + brimonidine
Iopidine
Apraclonidine
Alpha 2 agonist eye drop
Rhopressa
Netarsudil
Rho kinase inhibitor
Eye drop glaucoma
Xiidra
Lifitigrast
Chronic dry eye
Restasis
Cyclosporine eye drops
Chronic dry eye
Lumify
Brimonidine
Red eye
Ciprodex
Ciprofloxacin and dexamethasone ear drops
Lysine
Cold sores
Azeleic acid
Acne
Tazarotene
Retinoids for acne
No pregnancy
Absorica
Isotretinoin
Myorisan
Isotretinoin
Denavir
Penciclovir
Nizoral
Ketoconazole shampoo for dandruff
Latisse
Bimatoprost
Don’t use with other PG analogs
Upper lid only
At night
Protropic
Tacrolimus
Eczema / psoriasis
Not less than 2 y
Second line only risk for lymphoma
Elidel
Pimecrolimus
Eczema / psoriasis
No less than 2 y
2nd line only- risk lymphoma
Qbrexa
Glyco topical for sweating
Butenafine
Antifungal
Highly effective (so is terbinafine)
Lamisil
Terbinafine
Lotrimin
Butenafine, clotrimazole, miconazole
Antifungal
Desitin
Diaper rash
Also: hydrocortisone 0.5-1%, zinc oxide, petrolatum, a and d ointment
Anusol
Hydrocortisone for hemorrhoids
Mebendazole
Pinworm RX
Hepatotoxicity
Albenza
Albendazole
Pinworm RX
Hepatotoxicity
Ivermectin
Scabies- oral
Lice- sklice- topical!
not first line
Vanos
Fluocinonide topical
Lidex
Fluocinonide cream
Lariam
Mefloquine
Malaria
Arakoda
Tafenoquine
Malaria
Yellow fever details
No specific tx
No nsaids or Asa- bleeding
Yellow card only valid if vaccinated 10 days before arrival
-vaccine CI if egg allergy
Vimovo
Naproxen + esomeprazole
Yazmin, yaz
Contains drosperinone
Progestin only pills
Erin, camila, nora-BE
Clomiphene
Serm for infertility
ADR: hot flash, clotting, multiple eggs/births
Lupron
Leuprolide
Gonadotropin releasing hormone
Infertility
Also breast and prostate cancer
SC/IM
Technivie
Ombitasvir, paritaprevir, ritonavir
Viekira pak
Ombitasvir, paritaprevir, ritonavir, dasabuvir
Actonel
Risendronate
Daily, weekly, or monthly
Bonivia
Ibandronate PO: Monthly IV: q 3 month (Upright x 60 min) Don’t take missed dose if within 7 d of next dose
Reclast
Zolendronate IV
Osteoporosis
Zometa
Zolendronate IV once yearly
Hypercalcemia of malignancy
Evista
Raloxifene Serm Osteoporosis Decreases risk of breast CA Causes VTE, hot flashes
Duavee
Cong estrogens/bazedoxifene
- Serm
- Osteoporosis tx and hot flash tx
- Risk breast, ovarian, endometrial CA!!
- VTE risk
*for women with a uterus- even though it causes endometrial CA…
Miacalcin
Calcitonin nasal spray
- Osteoporosis last line
- malignancy risk
- can use for hypercalcemia of malignancy
- fridge
Forteo
Teriparatide
PTH analog
Osteoporosis
-fridge and light protect
Tymlos
Abaliparatide
PTH analog
Osteoporosis
Fridge and light protect
Prolia
Denosumab inj Rank-L Osteoporosis Caution: osteonecrosis of jaw (Xgeva for hypercalcemia)
Atelvia
Long acting risendronate
Weekly
Alora frequency
Estradiol patch
Twice weekly
Climara frequency
Estradiol patch
Weekly
Osphena
Ospemifene
Dyspareunia
Relpax
Eletriptan
Provera
Medroxyprogesterone
Addyi
Flibanserin Hypoactive sexual desire disorder (premenopausal only) ADR: fainting/hypotension! *no etoh!! *rems!/ medguide!! Caution cyp3a4 inhibitor
Stendra
Avanafil
Levitra
Vardenafil
Alprostadil
Muse, caverject
ED
Jalyn
Dutasteride + tamsulosin
Uroxatral
Alfuzosil
Alpha blocker for BPH
1A selective!
Qtc
Rapaflo
Silodosin
Alpha blocker
BPH
Proscar
Finasteride for BPH
Avodart
Dutasteride
5-alpha reductase inhibitor
BPH
Detrol
Tolterodine
Anticholinergic (OAB)
Trospium
Anticholinergic (OAB)
Vesicare
Solifenacin M3 anticholinergic (OAB)
Enablex
Darifenacin (OAB)
M3 anticholinergic
Toviaz
Fesoterodine M3 anticholinergic (OAB)
Savella
Milnacipran
SNRI
Fibromyalgia
Fetzima
Levomilnacipran
SNRI
Amitiza
Lupiprostone
Constipation, OIC
Lucemyra
Lofexidine
A-2 agonist for opioid withdrawal
Zostrix
Capsaicin
Frova
Frovatriptan
Amerge
Naratriptan
Maxalt
Rizatriptan
Zomig
Zolmitriptan
DHE, migranal
Dihydroergotamine
CI: with 3A4 inhibitors, pregnancy, HTN, CV
Aimovig
Erenumab monthly inj
Migraine ppx
Ajovy
Fremanezumab
Monthly inj
Migraine ppx
Emgality
Galcancezumab
Monthly inj
Migraine ppx
Migraine ppx
Prop, timolol (non selective), metop, valproate, topiramate, cgrp antagonists , Botox type-A
Treximet
Sumatriptan + naproxen
Zyloprim tox
Allopurinol
-rash!, hepatotoxicity, renal dose
Start with nsaid or colchicine for 3-6 months
Uloric
Febuxostate
Xanthine oxidase inhibitor
-risk CV death, hepatotoxicity, rash!
-use if can’t tolerate allopurinol
Zurampic
Lesinurad
Uricosuric for gout
*use only with XOI
*think renal
Duzallo
Lesinurad + allopurinol
Probenecid
Uricosuric for gout
Increase beta lactams
G6PD, renal, kidney stone, blood dyscrasia, don’t use with ASA
KrystexxA
Pegloticase
Uricase for gout
Anaphylaxis- premedicate!
G6PD deficiency
*don’t use with XOI or probenecid
Prevpac
Amo + clarithromycin + PPI
- all BID
- use this triple therapy on if <15% clarithromycin resistance- usually quadruple therapy (CAM/BMT QID + PPI BID)
Arthrotec
Diclofenac + misoprostol
Yosprala
Asa + omeprazole
ER
How to treat NSAID induced (gastric) ulcer
PPI x 8 weeks
Vytorin
Zetia + simvastatin
DNE 20 mg Simvastatin if crcl<60
Which bile acid sequestrants ok in preganancy
Colesevelam
Bile acid sequestrant with less interactions
Colesevelam
Cholestyramine and colestipol separation from other drugs
1-4 h before, 4-6 h after
Bile acid sequestrant and vitamins absorption
Decreases ADEK
Gemfibrozil interaction
Don’t give with statins or zetia
Which cholesterol class can cause gallbladder dx
Fibrates
Which b vitamin is niacin
B3
Best niacin to use
Niaspan- less flushing and hepatotoxicity compared to other CR and SR
How to prevent burping from fish oil
Keep in freezer- NOT fridge
Lopitamide (juxtapid) issues
Hepatotoxicity, pregnancy
Kynamro (mipomersen) issues
Hepatotoxicity
Which statins to take in evening
Simvastatin, fluvastatin IR, lovastatin IR (mevacor- dinner)
*lovastatin ER (altoprev- evening)
Altoprev
Lovastatin ER
Evening
Mevacor
Lovastatin IR
Dinner
Edarbi
Azilsartan
Bystolic
Nebivolol
B1 and NO
Milk of magnesium
Mag hydroxide
Osmotic
Caution- renal
Miralax
Osmotic
Glycerin
Fleet
Osmotic
*good for children
Lactulose
Osmotic
Stimulant laxatives
Senna, bisacodyl
30 mins after a meal
Amitiza
Lubiprostone
Constipation
Linzess
Linaclotide
Constipation
Trulance
Plecanatide
Constipation
Movantik
Naloxegol
PAMORA
Synproic
Naldemidine
PAMORA
Entereg
Alvimopan
pAMORa
Hospitalized pts- reduce risk of post operative ileus
Motegrity
Prucalopride
5ht4 agonist
Constipation
*suicidal ideation**
Bismuth
Diarrhea
Bentyl
Dicyclomine
Diarrhea
Anticholinergic
Viberzi
Eluxadoline
Mu-agonist (peripheral) for diarrhea
C4
don’t use in pt without gallbladder
Entocort EC
Budesonide for chrones
*also uceris
Apriso
Mesalamine
UC
Delzicol
Mesalamine
UC
Pentasa
Mesalamine
UC
Asacol
Mesalamine
UC
Lialda
Mesalamine
UC
Rowasa
Mesalamine enema
UC
Better for distal
Canasa
Mesalamine supp
UC
Better for distal
Sulfasalazine indication
UC, RA
Balsalazide
UC
Aminosalysilate
Olsalazine
UC
MTX non cancer indication
RA, CD
Stelara
Ustekinumab
CHrones
Tysabri
Natelizumab
Chrones
PML- REMs touch program
NS only, q4wk
Entyvio
Vedolizumab
Chrones and UC
PML
Cyclizine
Antihistamine for motion sickness
Bonine
Meclizine
Dimenhydrinate
Dramamine
Motion sickness
Semglee
Glargine
Rybelsus
Ozempic
Multaq
Dronedarone
Rythmol
Propafenone
Corvert
Ibutilide
*IV only!
Betapace
Sotalol
Tikosyn
Dofetilide
Adenocard
Adenosine
TPa stroke
- 3 h symptom onset
- 60 min arrival
- BP<185/110
- AC CI within 24 h
Conivaptan
Siadh/ hypervolemic hyponatremia
Vasopressin antagonist