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Top 400 Drugs > Bcps > Flashcards

Bcps Flashcards

1
Q

Istradefylline

A

Nourianz

Adenosine antagonist

Parkinsons

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2
Q

Opicapone

A

Ongentys

Comp inhibitor for PD

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3
Q

Ozanimod

A

Zeposia

MS

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4
Q

Ponesimod

A

Ponvory

MS

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5
Q

Simponimod

A

Mayzent

MS

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6
Q

Cladrabine

A

Mavenclad

MS

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7
Q

Dalfampridine

A

Ampyra

MS- improves walking

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8
Q

Dextromethorphan/quinidine

A

Psedobulbar

(May be needed in MS)

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9
Q

Lumateperone

A

Caplyta

Atypical antipsych

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10
Q

Other clozapine issues

A

Seizures, thermoregulation issues, myocarditis/cardiomyopathy, anticholinergic, severe constipation

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11
Q

Aripiprazole and brexpiprazole funny ADRs

A

Compulsive behaviors (gambling)

Akathisia

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12
Q

Levomilnacipran vs milnacipran

A

Levo: depression
Milnacipran: FM

Both snri

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13
Q

Vortioxetine (trintellix)

A

SSRI

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14
Q

TCAs tertiary v secondary

A

Tertiary: amitriptyline, imipramine (more selective for seratonin)

Secondary: nortriptyline, desipramine ( more selective for NE and less anticholinergic )

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15
Q

MAOIs

A

Non-selective: isocatboxazid, phenelzine, tranylcypromine

Selective b: selegiline patch

2 week washout when switching to antidepressant, or 4 wks for fluoxetine

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16
Q

Which antipsyches are approved for adjunct antidepressant

A

Aripiprazole, brexpiprazole, seroquel

Data for risperidone

Also olanzapine +fluoxetine for treatment resistant depression

17
Q

Lithium pregnancy

A

Avoid in first trimester if possible

18
Q

Drugs causing lithium tox

A

Ace, nsaid, diuretic,

Decreases lithium: theophyline

19
Q

Dayvigo (lemborexant)

A

orexin blocker

Insomnia

20
Q

Amifostine

A

Prevents nephrotoxicity from cisplatin

21
Q

Mesna

A

Ifosfamide and cyclophosphamide

Prevents hemorrhagic cycatitis

22
Q

Leucovorin

A

Give with mtx- rescues normal cells

Also with 5-FU- improves activity

Separate from glucarpidase

23
Q

Glucarpidase

A

Treats toxic mtx levels

Separate from leucovorin

Top 400 Drugs (4 decks)

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