Other bullous diseases Flashcards by Alex Chantara | Brainscape

Q

autoantigen of LABD

A

LAD-1 (120 kDa part of BPAG2) and/or LABD97

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Q

drugs that cause LABD

A

vancomycin

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Q

level of split on histo of LABD

A

subepidermal (looks similar to DH)

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Q

DIF LABD

A

linear IgA at BMZ

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Q

IIF/SSS of LABD

A

binding on epidermal side of split roof

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Q

autoantigen of EBA

A

type VII collagen

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Q

level of split of EBA

A

subepidermal (target is type VII collagen)

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Q

SSS of EBA

A

dermal side

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Q

antigen od dermatitis herpetiformis

A

epidermal transglutaminase (TG-3) and tissue transglutaminase

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Q

part of gluten that has the antigenic component

A

gliadin

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Q

level of split of DH + histo

A

subepidermal + microabscesses in dermal papillae

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Q

DIF of DH

A

granular IgA > C3 in dermal papillae

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Q

other dz’s a/e DH

A

thyroid disease

increased risk of small bowel lymphoma

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Q

HLA associations with DH

A

HLA-DQ2

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Q

sweat gland necrosis on histology

A

coma blisters

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