Other Bugs

Question 1

Spirochetes

Answer 1

• Treponema pallidum (Syphilis)
• Borrelia burgdorferi (Lyme disease)
  
  • Giemsa and silver stains
• Borrelia recurrentis (Relapsing fever)
  
  • Giemsa and silver stains
• Leptospira interrogans (Leptospirosis)
  
  • “ice tong” appearance
  • Shed in animal urine

Question 2

Rickettsia

Answer 2

• Rickettsia rickettsii (Rocky Mtn Spotted Fever)
  
  • Dermacentor ticks
• Rickettsia prowazekii (Epidemic typhus)
  
  • Flying squirrels –> lice –> humans
  • Centrifugal rash, vascular necrosis
• Rickettsia typhi (Endemic typhus)
  
  • Rodents –> fleas –> humans
• Coxiella burnetii (Q Fever)
  
  • Inhalation of spores –> atypical pneumonia
  • No rash, no arthropod transmission

Tx: doxy or chloramphenicol

Welix-Felix reaction uses Proteus vulgaris to diagnose Rickettsia (except Coxiella burnetii)

Question 3

Obligate intracellular bugs

Answer 3

• Rickettsia - replicates freely in cytoplasm
• Chlamydia - replicates within inclusion bodies

Question 4

Obligate aerobes

Answer 4

• Nocardia
• Pseudomonas aeruginosa
• Mycobacterium tuberculosis

“Nagging Pests Must Breath”

Question 5

Obligate anaerobes

Answer 5

• Clostridium
• Bacteroides
• Actinomyces

Lack catalase and/or superoxide dismutase

Question 6

Facultative intracellular bugs

Answer 6

• Salmonella
• Neisseria
• Brucella
• Mycobacterium
• Listeria
• Francisella
• Legionella
• Yersinia pestis