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Blood Bank: Spring 2024 > Other Blood Groups > Flashcards

Other Blood Groups Flashcards

1
Q

Glycophorin A/B on chromosome __

A

Chromosome 4

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2
Q

PIPK on chromosome ___

A

Chromosome 22

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3
Q

Glob on chromosome __

A

Chromosome 3

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4
Q

Kell on chromosome ___

A

Chromosome 7

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5
Q

Kidd on chromosome __

A

Chromosome 18

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6
Q

Duffy on chromosome __

A

Chromosome 1

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7
Q

Lutheran on chromosome __

A

Chromosome 19

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8
Q

PIP gene encodes

A

P1 and Pk proteins

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9
Q

Glob gene encodes

A

P protein

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10
Q

Duffy syntenic with

A

Rh

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11
Q

Lutheran linked with

A

Lewis genes (all the FUTs)

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12
Q

Antigens enhanced by enzymes

A
  • Kell
  • Rh
  • Kidd
  • Lewis
  • P/Glob
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13
Q

Antigens destroyed by enzymes

A
  • MNS
  • Duffy
  • Chido/Rogers
  • Xga
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14
Q

Antigens destroyed by DTT

A
  • Kell
  • Sometimes Lutheran
  • Cartwright
  • Dombrock
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15
Q

Antibodies against these blood antigen systems activate complement

A
  • Kidd
  • P system (anti-P, anti-PIPK, but NOT anti-P1)
  • Lewis
  • some anti-S
  • anti-I
  • Some anti-Lua/Lub
  • Rare anti-Fya/Fyb
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16
Q

List not-so-usual suspects not on antigram sheet because they are high//low antigen pairs Hint: there’s 9 systems

A
  • Dia/Dib
  • Yta/Ytb
  • Sc1/Sc2
  • Coa/Cob (Colton)
  • LWa/LWb
  • Cra,Tca/Tcb,Tcc (Cromer)
  • Kna/Knb, McCa/McCb (Knops)
  • Ina/Inb (Indian)
  • Ger 1-4 (Gerbich)
17
Q

List not-so-usual suspects not on antigram sheet because they’re clinically insignificant

A
  • Xga CD99
  • Chido/Rogers
  • Sda
18
Q

List not-so-usual suspects not on antigram sheet because they’re poor immunogens

A
  • Doa/Dob (Dombrock)
  • Oka (OK)
  • RAPH-MER2
  • JMH
19
Q

List not-so-usual suspects not on antigram sheet but the slides are unclear about why they’re not there

A
  • VEL (severe HDN, single Ag)
  • Jra (severe HDN, single g)
  • AnWJ (Hemophilus influenza receptor, auto-Ab, single Ag)
  • HLA (Bga, Bgb, Bgc)
20
Q

Systems that exhibit dosage

A
  • Duffy
  • Kidd
  • Rh
  • MNS

Blood Bank: Spring 2024 (10 decks)

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