Other

Question 1

What is cosolvent
Examples
How they work

Answer 1

Solvents that increase soulubilty of solutions

Ethanol, propylene glycol, cyclodextrins

Ethanol and propylene glycol increase water content of solution
Cyclodextrins increase water solubility, bioavailability and stability of peptide hormones

Question 2

What is the hormone that is produced but the hypothalamus to initiate sex hormones

Answer 2

GnRH

Question 3

What receptors are steroid hormones

Answer 3

Nuclear receptors

Question 4

What is the treatment for BPH

Answer 4

Finasteride

Question 5

Estrogen analogues which modification is used

Answer 5

Addition of ethinyl group at position 17
Use of pro drug esters at position 17

Question 6

Raloxifene MOA

Answer 6

Prevents the helix H12 loop from moving into the correct position
In breast tissue it inhibits ER- selective

Question 7

Chlamydia symptoms
Treatment for pregnancy
Complications

Answer 7

Fever, vaginal discharge, dysuria (painful urination), Lower abdominal pain, pelvic pain/ inflammation

Amoxicillin 500mg TDS 7 days
Erythromycin BD 14 days

Premature
Low weight birth
Infections in neonates
Baby can get conjunctivitis and pneumonia