Osteosarcoma Flashcards

1
Q

What are the predilection sites for osteosarcoma?

A

Proximal humerus
Distal radius
Distal femur
Proximal and distal tibia

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2
Q

What three features are noted on radiography of an osteosarcoma?

A

Cortical destruction
Loss of trabecular pattern
Sunburst- tumour bone extends into soft tissues

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3
Q

What tests are required for staging and diagnosis of osteosarcoma?

A

3 view chest radiography
+/- CT MRI

Jamshidi/FNA

Post amputation histopath

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4
Q

What are the features of metastasis of osteosarcoma?

A

Pulmonary metastasis are soft tissue opacity, there are occult metastasis in 95% cases

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5
Q

How is osteosarcoma treated?

A

Forequarter amputation
Coxofemoral disarticulation

Carboplatin +/- doxorubicin

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6
Q

What is the MST for osteosarcoma?

A

3-4 months after amputation

1 year with amputation and chemo

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7
Q

What is the follow up for osteosarcoma patients?

A

3 monthly clinical exam and chest radiographs

Death is usually due to metastasis, metastasectomy can be considered

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