MCTs Flashcards
1
Q
Well Differentiated
A
Hairless
Slow growing
Present for months
Solitary
2
Q
Poorly Differentiated
A
Large, fast growing
Ulcerated
Pruritic
Satellite nodules
3
Q
Indicators of aggression
A
Poorly differentiated
Local irritation
Poorly demarcated
Paraneoplastic signs
4
Q
What is the effect of a MCT that secretes histamine?
A
Stimulation of gastric H2
HCl oversecretion
Hypermotility
Ulceration in 35-80%
5
Q
What are the clinical signs associated with histamine secretion?
A
Vomiting
Anorexia
Abdominal pain
GI Haemorrhage
6
Q
How are MCTs staged?
A
FNA or excise mass
FNA draining lymph node
Abdominal Ultrasound- FNA liver or spleen if enlarged
7
Q
What is the metastatic rate based on Patnaik grading?
A
- Well differentiated, <10% metastasis, 2cm margins curative
- Intermediate, 20% metastasis, 2cm margins curative
- Poorly differentiated >80% mets
7
Q
What is the MST for MCT based on kuipel criteria?
A
High grade 4 months
Low grade 2 years
