Osteoporosis Flashcards
Define osteoporosis
decreased bone mass due to disruption of micro-architecture of bone that results in risk of fractures
How is bone mineral density measured and what is the threshold for osteoporosis?
DEXA; 2.5 S.D. below peak one mass at 20 y.o.
What is the softening of bone?
osteomalacia
What is decreasing of bone density?
osteoporosis
What is too little bone; low bone mass called?
osteopenia
What is primary osteoporosis?
Most common and not related to any underlying cause,
What leads to primary osteoporosis? (3)
- postmenopausal
- idiopathic
- senile (>70 y.o.)
What is secondary osteoporosis?
osteoporosis associated with other disease or medication.
What age can you get secondary osteoporosis?
any age
What two hormone deficiency can lead to primary osteop?
estrogen, testoterone
What excessive intake can lead to osteop?
vitamin A
Prolonged use of what three drugs can lead to secondary osteop?
- corticosteroid
- Heparin
- anticonvulsant
What is the most common metabolic bone disease?
osteop
What is the top 4 fracture sites due to osteop?
- vertebral
- wrist
- hip
- pelvic
What is the outer portion of the bone called and it makes up for what % of the bone in the body?
cortical; 80%
What is the spongy inner portion of the bone called?
trabecular
What age does bone mass peak?
25-35