Osteomyelitis Flashcards
Bacteria involved in hematogenous osteomyelitis?
Staph aureus, strep, gram neg
Bacteria involved in hematogenous osteomyelitis with sickle cell patients?
salmonella
Bacteria involved in direct implantation?
pseudomonas
Bacteria involved in contiguous?
Mixture. Staph, gram neg, strep, anaerobes… expect candida also, and foul smell
Bacteria involved in prosthetic joint infections?
Expect coagulase negative straph, strep… also expect biofilm formation.
Which type of osteomyelitis is more common in children?
Hematogenous, due to a previous bacteremia
What type of osteomyelitis is more common in adults?
Contiguous and Prosthetic Device infection
What’s a sequestrum?
Dead bone from the periosteum being damaged
What’s an involucrum?
New external bone formation reactionary to osteomyelitis damage
What are brodie’s abscesses?
Local abscesses in bone due to osteomyelitis
Why are biopsies and blood cultures often times not very sensitive for invading organism?
Patients are often times already on antibiotics by the time biopsy is done. This is especially true of patients with hematogenous osteomyelitis
What is the best test for early infections of osteomyelitis?
MRI imaging and WBC/Bone scans are much more sensitive than X-rays, which will often read negative unless very progressed or unless dealing with children who’s bones are otherwise expected to be fairly pristine and free of any major wear
What is usually required to treat prosthetic infection?
Often times, the prosthetic must be removed to treat. Biofilms are very challenging to treat
Are cultures of ulcerated contiguous osteomyelitis useful?
No. Often times many populations of flora are present. What may be biopsied at the ulcer site may be different than what is infecting the bone
What is slime?
The matrix produced by adherent microorganisms organized into a biofilm
