Osteology: Study of Bone Flashcards
The FOUR basic tissue types
1) Epithelial
2) Neural
3) Connective
4) Muscular
These are the bone-FORMING cells
Osteoblasts
These are the bone-NURTURING cells
Osteocytes
These are the bone-REMODELING cells
Osteoclasts
Cells are surrounded by or embedded in this fluid filled material
Matrix
Bones cells are embedded or surrounded by this type of matrix
Amorphous matrix
An amorphous matrix consists of the following substances
1) ground substance
2) collagen fibers
3) various minerals
This substance is rich in glycosaminoglycans (GAG’S) which includes chondroitan sulfate, keratin sulfate, and hyaluronic acid
Ground substance
These molecules are linear, non-branching, repeating disaccharide units. They are mainly found in the ground substance of bone.
Glycosaminoglycan’s (GAG’S)
These GAG’s are primarily found in bone
1) Chondroitin sulfate
2) Keratin sulfate
3) Hyaluronic acid
These are formed from the protein collagen and are located in the ground substance. These molecular units bond together in a linear sequence to form a fiber.
Collagen fibers
The primary type of collagen fiber found in bone
Type I collagen
Various chemical groups make up this INORGANIC part of the bone
Bone mineral
These molecules are stored in the matrix and serve to provide the RIGIDITY for bone
Calcium phosphate
Citrate
Carbonate ions
The MOST common deposit in bone that is a form of calcium phosphate.
Hydroxyapatite
Other mineral and chemical deposits in bone
1) Sodium
2) Magnesium
3) fluoride ions
4) lead (cation)
5) strontium (cation)
6) radium (cation)
States that bone will RESPOND to stressors. A bone will be deposited when and where it is needed and it will be resorbed when and where it is not needed.
Wolff’s Law
“Living bone” describes the ability of bone to….
1) HEAL
2) REMODEL (under stressors as diverse as anxiety, tension or pressure
3) AGE
Bone is embryologically derived from one of two CONNECTIVE tissue types
1) Mesenchyme (intramembranous)
2) Cartilage (endochondral)
Mesenchyme and cartilage will convert to osteoblast-like cells during this time period
2nd to 5th month IN utero
This is when the bone forms within the primitive connective tissue or MESENCHYME. Characteristic of most bones of the SKULL and part of the CLAVICLE
Intramembranous ossification
Intramembranous ossification occurs during this time period
2nd to 3rd month IN utero
Bones that undergo INTRAMEMBRANOUS ossification (from mesenchyme)
1) Nasal
2) Palatine
3) Vomer
4) Lacrimal
5) Zygomatic
6) Maxilla
7) Frontal
8) Parietal
9) Most of the mandible and clavicle
10) Squama of temporal and occipital bones
11) greater wing of sphenoid
This is when bone develops within CARTILAGE. Characteristic of the remaining bones of the skull and the rest of the skeleton (everything else)
Endochondral ossification
Endochondral ossification occurs during this time period
2nd to 5th month IN utero
Centers for ossification in the SKULL in CARTILAGE template
Chondrocranium
Bones derived from the CHONDROCRANIUM
1) inferior nasal concha
2) ethmoid
3) sphenoid
4) part of mandible
5) Temporal and occipital bones
Centers of ossification within cartilage that occur BEFORE birth
Primary centers of ossification
Centers of ossification within cartilage that occur AFTER birth
Secondary centers of ossification
Solid, dense bone that covers the EXTERIOR of all bones forming the skeleton
Compact (cortical) bone
Bone that makes up the INTERIOR of all bones forming the skeleton
Spongy (cancellous, trabecular) bone
A space that exists within the interior bony framework (Spongy bone)
Marrow cavity
When one bone articulates with another bone in a fluid-filled joint, the compact bone is covered by this type of cartilage
Subchondral bone
Thin layer of cells and fibers that covers the NON-articular surface of any bone
Periosteum
Internal fibro-cellular layer lining the Spongy bone
Endosteum
There is a great deal of _________ in bone that accounts for the disparity in size, appearance, and or shape of individual bones. There are 4 general types of this
Variability
This is GENDER variation that has inherent differences between the same bone in males and females
Sexual dimorphism
GROWTH or age variation. Bone will differ based on the AGE of the individual
Ontogenetic variation
Ethnic background. The location of origin, select community of origin, or the ethnic (racial) background influence the bone variation
Geographic or population-based variation
Individual variation. These are differences between individuals of the same sex, age, and geographic population differences are evident. There are no true identical persons
Idiosyncratic variation
Bone classification in which the length of the bone is GREATER than the breadth
Long bones
This bone consists of a DIAPHYSIS and two EPIPHYSES
Long bones
Name of the shaft of long bones
Diaphysis