OSTEOLOGY- Cells, matrix, ossification, bone density, bone variation Flashcards
What are the four basic tissues of the human body?
epithelial, muscle, neural, and connective tissue
What is osteology?
the study of bone
What are the three primary cell types of bone?
osteoblasts, osteocytes, and osteoclasts
What is the function of each type of bone cell?
osteoblast - form bone
osteocyte - maintain or nurture bone
osteoclast - remodel bone
What are the bone cells embedded in?
an amorphous matrix consisting of ground substance, protein fibers and various minerals
What is the primary constituent of the ground substance?
glycosaminoglycans
What types of glycosaminoglycans predominant in bone?
chondroitin sulfates, keratin sulfates, and hyaluronic acid
What is the principal type of protein fiber in bone?
collagen type 1
What are the primary constituents of the bone mineral?
calcium, phosphate, citrate and carbonate ions
what is the most frequently described deposit in bone?
hydroxyapatite
Bone is also the repository for what additional ions?
sodium, magnesium, fluoride, lead, strontium and radium
What is Wolff’s Law as it pertains to bone?
living tissue will respond to stressors; bone is formed or absorbed in response to various stressors
What three responses of “living” bone were stressed in class?
it has the ability to heal, to remodel under stressors, and to age
Bone is the embryological derivative of which specific connective tissues?
mesenchyme and/or cartilage
What is the name given to the pattern of ossification in mesenchyme?
intramembranous ossification