osteointegration Flashcards

1
Q

new bone forms on old bone

A

distance

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2
Q

bone forms on surface of implant

A

contact

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3
Q

osteogenic become what

A

osteoblasts

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4
Q

what do osteoblasts do (contact)

A

lay down new bone matrix on implant surface

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5
Q

what is first to be secreted by osteoblasts

A

cement line (calcified collagen-free matrix)

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6
Q

what does cement line separate

A

new bone from old bone

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7
Q

what forms after cement line

A

collagenous and mineralized ECM of bone

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8
Q

what is more stabilizing for implant

A

contact osteogenesis

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9
Q

what happens after osteogenic cells move to old bone surface

A

they become osteoblasts and then become polarized

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10
Q

osteocytes become ____ in the bone matrix (distance)

A

buried

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11
Q

why do the osteocytes die

A

they are cut off from their vascular supply as they get buried in their own matrix

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12
Q

integrity of the bone is maintained by

A

osteogenic cells replace osteocytes that get buried

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13
Q

what separated the implant from bone in distance

A

osteoblasts

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14
Q

why cant osteoblasts migrate to the surface

A

their processes are buried in matrix

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15
Q

contact is the sum of what

A

osteoconduction and bone formation

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16
Q

what is the first step after blood clotting

A

platelets impact the surface

17
Q

what do platelets do at the implant

A

release GF and cytokines

18
Q

what do GF and cytokines do

A

increase other platelet activation

19
Q

what gets activated after platelets

A

white blood cells