Osteoarticular Flashcards

1
Q

componentes sutancia osteoide

A

colágeno I, osteonectina, osetopontina y osteocalcina, mucopolisacáricos

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2
Q

origen osteoblastos y osteocitos

A

Mesenquimal

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3
Q

origen osteoclastos

A

hematopoyético

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4
Q

pico máx de masa osea

A

30-35 años

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5
Q

OP recambio disminuido

A

senil:déficit Vit D (primaria), fractura cadera

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6
Q

Fases remodelado ósea

A

1) Fase quiescente
2) activación
3) reclut osteoclastos
4) Reabsorción (laguna howship)
5) Acoplamiento
6) Reclut osteoblastos
7) Síntesis sust osteoide
8) Mineralización

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7
Q

OP: recambio aumnetado

A

postmenopáusica: deficit estrógenos (secundaria), fractura vertebral

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8
Q

Marcador de remodelado (formación)

A

fosfatas alacalina, osteocalcina y PINP

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9
Q

Marcador de remodelado (resorción)

A

prodcutos derivados degradación colágeno CTX

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10
Q

T-score osteopenia

A

< -1,0

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11
Q

T-score osteoporosis

A

< -2,5

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12
Q

T-score osteoporosis grave

A

< -2’5 + FRACTURA

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13
Q

T-score CN

A

> -1’0

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14
Q

recambio diario de calcio

A

700 mg

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