Osteoarthritis Flashcards
1
Q
Definition
A
Tear - Micro-damage to joint
Flare - Inflammatory response
Repair - Continued response
2
Q
Epidemiology
A
Most common joint problem
60% of the over 60s
3
Q
Pathophysiology
A
Synovial hypertrophy Subchondral changes (thickening) Joint effusion
4
Q
Etiology/Risk Factors
A
Repetitive microtrauma: Mechanical imbalance (abnormal anatomy) Interarticular fractures Ligament rupture Meniscal injury Occupation Prescient heavy physical activity Obesity (increased load & pro inflammatory response)
5
Q
Presentation
A
45 years old
Activity related joint pain
Possibly a tiny amount of morning related stiffness
Slow deterioration
6
Q
Lab Work Up
A
.
7
Q
Imagining
A
X-ray (no changes initially)
8
Q
Complications
A
Depression
Pain modifying ADLs
9
Q
Differential Diagnosis
A
RA
Septic arthritis
Malignancy
Gout
10
Q
Treatment
A
Selfmanagement:
- Weight loss
- Reduction in certain activities
- Muscle strengthening
- Sleep
Analgesics (oral/topical/injections): Paracetamol NSAIDs Capsaicin Steroid Hyaluronic acid
Thermotherapy
Electrotherapy (strengthen muscles)
Spinting
Surgery:
- All treatments should be tried
- Only for significant pain
- Joint replacement
AVOID:
Acupuncture
Glycosamine
Chondrotin
11
Q
Prognosis
A
.
12
Q
Histology
A
.
