Osteoarthritis Flashcards

1
Q

What is osteoarthritis?

A

Degenerative disease of the joints resulting from wear of the articular cartilage, which may lead to secondary changes in the underlying bone

Can be primary, or secondary to abnormal load to the joint or damage to the cartilage from inflammation or trauma

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2
Q

What percentage of individuals over the age of 60 years old have some form of osteoarthritis?

A

10-15%

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3
Q

Why does osteoarthritis occur?

A
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4
Q

What anatomical problems can cause the development of osteoarthritis?

A
  • Dysplasia
  • SUFE
  • Perthes
  • Osteodysplasia
  • Impingement lesions
    • Mechanical mismatch
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5
Q

What are the traumatic causes of osteoarthritis?

A
  • Direct joint trauma
  • Malalignment
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6
Q

What diseases can cause osteoarthritis?

A
  • Haemophilia
  • Haemochromatosis
  • Hypermobility syndrome
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7
Q

What risk factors can predispose to the development of osteoarthritis?

A
  • Obesity
  • Diet
  • Bone density
  • Age
  • Exercise
  • Occupation
  • Gender
  • Ethnicity
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8
Q

What are the symptoms of osteoarthritis?

A
  • Pain/stiffness
    • Stiffness for a few minutes in the morning
    • RELIEVED BY REST
    • Progressive from weight bearing to at rest/at night if very severe
  • Swelling
  • Decreased ROM
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9
Q

What are the general clinical signs of osteoarthritis?

A
  • Muscle Wasting
  • Palpable/Audible Crepitus
  • Joint effusion
  • Joint instability
  • Warmth over affected joint
  • Visible Deformity
  • Abnormal gait
  • Decreased active/passive movment ROM
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10
Q

What is a Bouchard’s node?

A

Osteoarthritic enlargement of the PIP

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11
Q

What are Heberden’s nodes?

A

Osteoarthritic enlargements of the DIP

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12
Q

What does arthritis mean?

A

Inflammation of a/multiple joints

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13
Q

What does arthropathy mean?

A

Joint pathology; any disease of the joint

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14
Q

What does arthrosis mean?

A

A term for a degenerative disease of the joint where the cartilage lining the joint erodes over time. Usually used for osteoarthritis.

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15
Q

What are symptoms of osteoarthritis in the knee?

A
  • Pain - on walking on uneven ground/ascending/descending stairs
    • Anterior/medial pain most common
  • Stiffness - after inactivity, resolves in <30 mins
  • Decreased ROM
  • Swelling
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16
Q

What are symptoms of OA in the hip?

A
  • Pain - groin on exercise
    • Referred pain - buttock, anterior thigh, knee
  • Decreased ROM
  • Stiffness
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17
Q

What is the pathophysiology of Osteoarthritis?

A
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18
Q

What are the clinical features of OA in the hand?

A
  • Pain
  • Swelling/stiffness
  • Restricted ROM
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19
Q

On examination, what is one of the early signs of the development of osteoarthritis of the hip?

A

Internal rotation

20
Q

What would you see on examination in someone with knee OA?

A
  • Antalgic gait
  • Varus/Valgus deformity - more often varus
  • Joint effusion
  • Joint-line tenderness
  • Crepitus
  • Quad muscle wasting
  • Bony deformity
  • Reduced ROM
21
Q

On examination of the hand, what would you see in osteoarthritis of the hand?

A

Bilateral

  • Herberden’s/bouchards nodes
  • Squaring of the hand
  • Subluxation of 1st CMCJ
22
Q

On examination, what signs would you see in someone with hip osteoarthritis?

A

Unilateral - more often than bilateral

  • Antalgic Gait
  • Global deficit in ROM - internal rotation early on, external rotation/abduction/adduction later
  • Fixed flexion deformity
  • Limb shortening
  • Quad/gluteal muscle weakness +/- wasting
23
Q

What is the following?

A

Bouchard’s Node

24
Q

What are the following?

A

Heberden’s Nodes

25
Q

What is the following deformity?

A

Genu Valgum - Valgus deformity

Distal point deviates away from the midline of the proximal point

26
Q

What is the following deformity?

A

Genu Varum - Varus deformity

Distal point deviates towards the midline of the proximal point

27
Q

What is the following deformity?

A

Squaring of the hand - 1st CMCJ

28
Q

How would you investigate someone that you suspect has osteoarthritis of a joint?

A

Imaging

  • X-ray
  • MRI (early)
  • Bone Scan
  • CT
29
Q

What findings on an X-ray would indicate osteoarthritis?

A
  • Loss of joint space - loss of articular cartilage
  • Osteophytes - extra bone formed to take extra load
  • Subchondral Cyst formation - change of bone to cartilaginous tissue due to load change
  • Sub-chondral sclerosis - increased whitening of the bone on x-ray due to hardening of bone
30
Q

The following radiograph was taken of someone with suscpected osteoarthritis in the knee. What findings are circled in the image?

A

Osteophytes

31
Q

The following radiograph was taken from someone with suspected osteoarthritis of the knee. What radiological finding is circled?

A

Loss of joint space

32
Q

The following radiograph was taken from someone with suspected osteoarthritis of the hip. What radiographic finding is circled?

A

Subchondral cyst

33
Q

The following radiograph was taken from someone with suspected osteoarthritis. What radiographic finding is circled?

A

Subchondral sclerosis

34
Q

What is the differential diagnosis of someone with joint pain, stiffness and decreased ROM?

A
  • Bursitis
  • Gout
  • Pseudogout
  • Rhematoid Arthritis
  • Psoriatic arthritis
  • Avascular necrosis
  • Internal derangements (e.g. meniscal tears)
35
Q

What general measures would you take in the management of someone with joint osteoarthritis?

A
  • Patient education - diagnosis, expectations
  • Physiotherapy
  • Activity modification
  • Offloading support - crutches, stick, zimmer
  • Lifestyle - weight loss
36
Q

How would you manage pain in osteoarthritis?

A

Therapeutic ladder

  • Paracetamol/topical NSAIDs
  • Oral NSAIDs
  • Opiates
37
Q

What other medical therapies (besides pain management) could be used to manage someone with osteoarthritis?

A

Injection Therapies

38
Q

What types of inection therapies can be used in osteoarthritis?

A
  • Steroid- reduces inflammation, 6 week effects
  • Hyaluronic acid - Restoration of elastovicous properties, Anti-inflammatory, Analgesic
  • Platelet rich plasma - Stimulates hyaluronic acid production
39
Q

What is the definition of arthroplasty?

A

Surgical refashioning of a diseased joint to relieve pain and to maintain/regain movement

40
Q

What are the different types of arthroplasty surgery?

A
  • Excision arthroplasty - excision of enough bone to create a gap at which movement can occur
  • Hemiarthroplasty - One sided joint replacement with erosion opposing surface. (e.g. only femoral head, not acetabulum as well)
  • Uni-compartmental Arthroplasty - Mainly knee (medial knee)
  • Resurfacing - Hip capsule and femoral head. 9 year follow up
  • Total Joint arthroplasty - Both sides joint replacement
41
Q

What is an osteotomy?

A

Surgical procedure to cut a bone into two parts, followed by realigment of the ends of the bone to allow healing - changes biomechanics of the joint

Example - osteotomy of the humerus

42
Q

What is surgical debridement?

A

Process of cleaning an open wound by removal of foreign material and dead tissue, so that healing can occur without hindrance

43
Q

What does microfracture surgery involve?

A

Articular cartilage repair surgical technique that works by creating tiny fractures in the underlying bone. This causes new cartilage to develop from a so-called super-clot

44
Q

What is arthrodesis?

A

Artificial Ankylosis”

The fusion of bones across a joint space by surgical means, which eliminates movement

Performed when a joint is very painful, highly unstable, grossly deformed or chronically infected

Can use cement, or can be fixated uncemented (e.g titanium implant)

45
Q

What are the two classes of surgical interventions in the management of osteoarthritis?

A
  • Joint sparing
  • Joint replacing