Osteoarthritis Flashcards

1
Q

Aetiology of OA

A

Mechanical “wear + tear”
localised loss of cartilage
remodelling of adjacent bone
associated inflammation

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2
Q

List 5 common RFs for OA

A

AGE
F > M
FH
Previous trauma of joint
Hypermobility of joint
Obesity

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3
Q

Typical joints affected in OA

A

Large weight-bearing joints (knee, hip)
Carpometacarpal joint
DIP, PIP joints

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4
Q

3 features of classic OA history

A

Pain following use, improves with rest
Unilateral Sx
No systemic upset

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5
Q

X-ray features of OA

A

Loss of joint space (affects distal joints more)
Osteophytes forming at joint margins
Subchondral sclerosis
Subchondral cysts

(LOSS)

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6
Q

3 risk factors for hip OA

A

F > M (2:1)
Obesity
DDH

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7
Q

Give 3 red flag features that suggest an alternate diagnosis to hip OA

A

Rest pain
Night pain
Morning stiffness > 2h

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8
Q

What tool is commonly used to assess severity of hip OA?

A

Oxford Hip Score

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9
Q

Describe investigations for hip OA

A

If features are typical: clinical dx
Otherwise: plain x-rays are first-line

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10
Q

Describe management of hip OA

A

Analgesia PO
Intra-articular injections (short-term benefit)
Total hip replacement remains the definitive Tx

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11
Q

List 4 peri-operative complications of total hip replacement

A

VTE
Intraoperative fracture
Nerve injury
Surgical site infection

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12
Q

What reduces risk of VTE post total hip replacement?

A

LMWH for 4w following op

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13
Q

List 4 post-op complications of total hip replacement

A

Leg length discrepancy
Posterior dislocation
Aseptic loosening
Prosthetic joint infection

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14
Q

Describe posterior dislocation of a total hip replacement

A

May occur during extremes of hip flexion
Presents acutely with a ‘clunk’, pain + inability to weight bear
OE: internal rotation + shortening of the affected leg

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15
Q

Post-hip replacement, what advice is given to reduce risk of dislocation?

A

Avoid flexing hip > 90 degrees
Avoid low chairs
Do not cross your legs
Sleep on back for the first 6w

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16
Q

What is the most common reason for revision of a total hip replacement?

A

Aseptic loosening

17
Q

2 Risk factors for hand OA

A

F > M (3:1)
Occupation e.g. cotton workers + farmers

18
Q

How is hand OA most commonly detected?

A

Radiologic signs are more common than Sx

19
Q

What does hand OA increased risk of?

A

Future hip + knee OA

20
Q

Which joints of the hand are most commonly affected in OA?

A

1st Carpometacarpal (CMCs) +
Distal interphalangeal (DIPJs) >
Proximal interphalangeal (PIPJs)

21
Q

Describe symptoms of hand OA

A

Intermittent joint ache. Provoked by movement + relieved by rest
Stiffness: worse after long periods inactivity (waking up), lasts a few mins

22
Q

List signs of hand OA

A

Painless nodes
Squaring of the thumbs
Wasting of thenar muscles at base of thumb

23
Q

What are the painless nodes that develop in hand OA called? What causes these?

A

Bouchard’s nodes: PIPJ
Heberden’s nodes: DIPJ
Result of osteophyte formation

24
Q

What causes squaring of the thumbs in hand OA?

A

Subluxation of CMC (partial dislocation), formation of osteophytes, + remodelling of the bones.
Results in fixed adduction of thumb.

25
Describe initial management of OA
All should be offered help with weight loss, given advice about local muscle strengthening exercises + general aerobic fitness TOP NSAIDs first-line (particualrly beneficial for OA of knee or hand)
26
Describe second line management of OA
NSAIDs PO + PPI Walking aids (knee/ hip OA) Intra-articular steroid injection if standard Tx ineffective (short term relief 2-10w) Consider referral for joint replacement
27
Describe use of paracetamol or weak opioids in OA
NOT recommended unless only used infrequently for short-term pain relief AND all other pharmacological Tx are CI, not tolerated or ineffective