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Radiography Abbreviations > Ossification > Flashcards

Ossification Flashcards

1
Q

What is ossification?

A

Formation of bone by osteoblasts

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2
Q

What do osteoblasts do?

A

Responsible for forming new bone, grow and heal existing ones

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3
Q

What ate osteoclasts?

A

Large cells that dissolve the bone, they come from bone marrow and are related to white blood cells. Initiate normal bone remodelling.

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4
Q

What are osteocytes?

A

Regulate mineral deposition and chemistry at the bone matrix level- bone health

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5
Q

What are chondrocytes?

A

Produce cartilage matrix, surrounded by collagenous fibre to make cartilage strong but flexible

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6
Q

What are the two types of ossification?

A

Intramembranous and enochondral ossification

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7
Q

What is intramembranous ossification?

A

Making bone between connective tissue. Forms flat bones.

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8
Q

What is endochonral ossification?

A

Making bone in cartilage, form all other bones from hyline cartilage model

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9
Q

Whats the first step in intramembranous ossification?

A

An ossification centre forms at mesenchyme. Mesenchymal cells differentiate into osteoblasts (cause growth)

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10
Q

What is second step in intramembranous ossification?

A

Soft matrix deposited. Osteiblasts lay down osteoid around blood vessels (traveculae pattern) Some osteoblast become osteocytes because they are trapped in hard matrix

Collagen lots

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11
Q

What is the third step in intramembranous ossification?

A

Matrix mineralised by calcium and phosphate - hardens

Stem cells in blood populate trabecluae

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12
Q

What is the fourth step in intramembranous ossification?

A

Spongy bone forms

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13
Q

What is the fifth step in intramembranous ossification?

A

Periosteum forms from mesenchyme

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14
Q

What is the sixth step in intramembranous ossification?

A

Compact bone forms

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15
Q

What is the first step of endrochondral ossification?

A

Bony collar forms in primary ossification centre

Diaphysis - middle of bone

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16
Q

What is the second step of endrochondral ossification?

A

Cartilage grows and ossification traps chondrocytes, these then die off from not getting nutrients

17
Q

What is the third step of endrochondral ossification?

A

Osteoblasts carve out medullary cavity (get rid of matrix) spongy bone forms

18
Q

What is the fourth step of endrochondral ossification?

A

Secondary ossification centre develop in epiphysis. Epiphyseal plate left.

Same process occurs - ossification~cartilage~death~spongy bone formation

Radiography Abbreviations (3 decks)

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