Osmosis Flashcards
osmosis
facilitated and passive diffusion
facilitated = aquaporin channels
passive = doesnt require energy moves down osmotic gradient
osmotically active
non permeant solutes are osmotically active as they establish the osmotic gradient and promote the movement of water
requirements for osmosis
conc dif between 2 sides of membrane
membrane impermeable to at least 1 solute
osmotic pressure
the pressure generated when water moves across a semi permeable, non moveable membrane to equilibrate solvent concentration
measuring osmotic pressure
measuring force generated
osmotic pressure ratio
solute : solvent
i.e. total number of dissolved solute non permeant molecules in solution that determines the osmotic pressure
osmolarity equation
osmolarity (OsM/L) = molarity (mol/L) x number of particles per molecule
osmolarity of fluids in the human body
280 - 296 mOsM/L
Osmolarity vs Tonicity
osmolarity doesnt provide information about how particles behave (their nature) or what happens to a cell in solution but it does provide units of measurement.
Tonicity predicts the movement of the molecules across the membrane by predicting nature of solutes in solution to the cell. Tonicity describes what happens to cell volume in solution but tonicity has NO units of measurement is a comparative term ONLY
Tonicity
specifically depends on the concentration of non penetrating solutes e.g. NaCl
penetrating solutes
will leave cell by diffusion with no movement of water because water is not needed to make up the conc of solutes in solution
non penetrating solutes
water will move into the compartment that has the higher conc of non penetrating solutes
hypertonic solution
contains more non penetrating solutes than cell
hypotonic solution
contains less non penetrating solutes than cell
hyper osmotic volume contraction
diabetes insipidus or sweating/fever
free water loss from the body due to ADH malfunction