Cellular transport Flashcards
simple diffusion
high to low conc
uncharged and hydrophobic solutes
e.g. gasses, alcohol, steroids and some general anaesthetics
facilitated diffusion + osmosis
high to low conc via integral proteins e.g. aquaporin for water
bulk transport
endocytosis + endocytosis
Ficks First Law of diffusion
consider:
membrane surface which determines how rapid diffusion is
how lipid soluble solute is
molecular size (larger the size the slower)
concentration gradient
active transport
lipid insoluble and charged molecules moving via integral membrane bound proteins using ATP or electrogenic pump
2 types:
channel proteins
carrier proteins
channel proteins
gated channels e.g. ion channels open channels (aquaporins but this is facilitated diffusion)
carrier proteins
uniporters which span the width of the membrane but are only open at one end at any one time
e.g. glucose transporters and amino acid transporters
secondary active transport
utilises ion conc gradient generated by primary active transport ATPases as potential energy source to move other ions against conc gradient i.e. indirectly dependent on ATP transporters include: symporter antiporter
symporter
co transporter and transports another substance into or out of the cell when coupled with movement of ion in the SAME DIRECTION (i.e. using Na/K ATPase)
antiporter
exchanger where substances will move in opposite direction to the direction of the primary active transporter.